Deborah Hung | Genetics

Deborah Tan Hung, M.D., Ph.D.

Associate Professor of Genetics

Phone:

617/643-3117

Fax:

617/726-6893

dhung@partners.org

Tabs

Publications

Whole-organism phenotypic screening for anti-infectives promoting host health.

Deborah Tan Hung, M.D., Ph.D.

Nature chemical biology, March 19, 2018

Clatworthy AE, Romano KP, Hung DT

Link to abstract on PubMed

The Expanding Diversity of Mycobacterium tuberculosis Drug Targets.

Deborah Tan Hung, M.D., Ph.D.

ACS infectious diseases, February 15, 2018

Wellington S, Hung DT

Link to abstract on PubMed

Continuous and High-Throughput Electromechanical Lysis of Bacterial Pathogens Using Ion Concentration Polarization.

Deborah Tan Hung, M.D., Ph.D.

Analytical chemistry, December 15, 2017

Kim M, Wu L, Kim B, Hung DT, Han J

Link to abstract on PubMed

scDual-Seq: mapping the gene regulatory program of Salmonella infection by host and pathogen single-cell RNA-sequencing.

Deborah Tan Hung, M.D., Ph.D.

Genome biology, October 27, 2017

Avital G, Avraham R, Fan A, Hashimshony T, Hung DT, Yanai I

Link to abstract on PubMed

Metagenomic Sequencing of an Echovirus 30 Genome From Cerebrospinal Fluid of a Patient With Aseptic Meningitis and Orchitis.

Deborah Tan Hung, M.D., Ph.D.

Open forum infectious diseases, July 28, 2017

Piantadosi A, Mukerji SS, Chitneni P, Cho TA, Cosimi LA, Hung DT, Goldberg MB, Sabeti PC, Kuritzkes DR, Grad YH

Link to abstract on PubMed

A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.

Deborah Tan Hung, M.D., Ph.D.

Nature chemical biology, July 3, 2017

Wellington S, Nag PP, Michalska K, Johnston SE, Jedrzejczak RP, Kaushik VK, Clatworthy AE, Siddiqi N, McCarren P, Bajrami B, Maltseva NI, Combs S, Fisher SL, Joachimiak A, Schreiber SL, Hung DT

Link to abstract on PubMed

Systematic, multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulence.

Deborah Tan Hung, M.D., Ph.D.

PLoS pathogens, May 15, 2017

Barczak AK, Avraham R, Singh S, Luo SS, Zhang WR, Bray MA, Hinman AE, Thompson M, Nietupski RM, Golas A, Montgomery P, Fitzgerald M, Smith RS, White DW, Tischler AD, Carpenter AE, Hung DT

Link to abstract on PubMed

Nucleic acid detection with CRISPR-Cas13a/C2c2.

Deborah Tan Hung, M.D., Ph.D.

Science (New York, N.Y.), April 13, 2017

Gootenberg JS, Abudayyeh OO, Lee JW, Essletzbichler P, Dy AJ, Joung J, Verdine V, Donghia N, Daringer NM, Freije CA, Myhrvold C, Bhattacharyya RP, Livny J, Regev A, Koonin EV, Hung DT, Sabeti PC, Collins JJ, Zhang F

Link to abstract on PubMed

Ribosomal mutations promote the evolution of antibiotic resistance in a multidrug environment.

Deborah Tan Hung, M.D., Ph.D.

eLife, February 21, 2017

Gomez JE, Kaufmann-Malaga BB, Wivagg CN, Kim PB, Silvis MR, Renedo N, Ioerger TR, Ahmad R, Livny J, Fishbein S, Sacchettini JC, Carr SA, Hung DT

Link to abstract on PubMed

Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks.

Deborah Tan Hung, M.D., Ph.D.

Proceedings of the National Academy of Sciences of the United States of America, January 17, 2017

Cerqueira GC, Earl AM, Ernst CM, Grad YH, Dekker JP, Feldgarden M, Chapman SB, Reis-Cunha JL, Shea TP, Young S, Zeng Q, Delaney ML, Kim D, Peterson EM, O'Brien TF, Ferraro MJ, Hooper DC, Huang SS, Kirby JE, Onderdonk AB, Birren BW, Hung DT, Cosimi LA,...

Link to abstract on PubMed

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