George Church headshot

George Church, Ph.D.

Robert Winthrop Professor of Genetics, Harvard Medical School
REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease.
Authors: Authors: Meyer K, Feldman HM, Lu T, Drake D, Lim ET, Ling KH, Bishop NA, Pan Y, Seo J, Lin YT, Su SC, Church GM, Tsai LH, Yankner BA.
Cell Rep
View full abstract on Pubmed
Establishing a Cell-Free Vibrio natriegens Expression System.
Authors: Authors: Wiegand DJ, Lee HH, Ostrov N, Church GM.
ACS Synth Biol
View full abstract on Pubmed
Developmental barcoding of whole mouse via homing CRISPR.
Authors: Authors: Kalhor R, Kalhor K, Mejia L, Leeper K, Graveline A, Mali P, Church GM.
Science
View full abstract on Pubmed
Biosensor libraries harness large classes of binding domains for construction of allosteric transcriptional regulators.
Authors: Authors: Juárez JF, Lecube-Azpeitia B, Brown SL, Johnston CD, Church GM.
Nat Commun
View full abstract on Pubmed
An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance.
Authors: Authors: Bester AC, Lee JD, Chavez A, Lee YR, Nachmani D, Vora S, Victor J, Sauvageau M, Monteleone E, Rinn JL, Provero P, Church GM, Clohessy JG, Pandolfi PP.
Cell
View full abstract on Pubmed
Enabling multiplexed testing of pooled donor cells through whole-genome sequencing.
Authors: Authors: Chan Y, Chan YK, Goodman DB, Guo X, Chavez A, Lim ET, Church GM.
Genome Med
View full abstract on Pubmed
From Designing the Molecules of Life to Designing Life: Future Applications Derived from Advances in DNA Technologies.
Authors: Authors: Kohman RE, Kunjapur AM, Hysolli E, Wang Y, Church GM.
Angew Chem Int Ed Engl
View full abstract on Pubmed
Adaptive evolution of genomically recoded Escherichia coli.
Authors: Authors: Wannier TM, Kunjapur AM, Rice DP, McDonald MJ, Desai MM, Church GM.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Spontaneous CRISPR loci generation in vivo by non-canonical spacer integration.
Authors: Authors: Nivala J, Shipman SL, Church GM.
Nat Microbiol
View full abstract on Pubmed
The Future of Multiplexed Eukaryotic Genome Engineering.
Authors: Authors: Thompson DB, Aboulhouda S, Hysolli E, Smith CJ, Wang S, Castanon O, Church GM.
ACS Chem Biol
View full abstract on Pubmed