Alexander Gimelbrant headshot
Alexander Gimelbrant, Ph.D.
Associate Professor of Genetics
MaGIC: a machine learning tool set and web application for monoallelic gene inference from chromatin.
Authors: Authors: Vinogradova S, Saksena SD, Ward HN, Vigneau S, Gimelbrant AA.
BMC Bioinformatics
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KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.
Authors: Authors: Hinohara K, Wu HJ, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, Rai G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrant AA, Michor F, Polyak K.
Cancer Cell
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KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.
Authors: Authors: Hinohara K, Wu HJ, Vigneau S, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, Rai G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrant AA, Michor F, Polyak K.
Cancer Cell
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High prevalence of clonal monoallelic expression.
Authors: Authors: Vigneau S, Vinogradova S, Savova V, Gimelbrant A.
Nat Genet
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Risk alleles of genes with monoallelic expression are enriched in gain-of-function variants and depleted in loss-of-function variants for neurodevelopmental disorders.
Authors: Authors: Savova V, Vinogradova S, Pruss D, Gimelbrant AA, Weiss LA.
Mol Psychiatry
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Tumor-suppressor genes that escape from X-inactivation contribute to cancer sex bias.
Authors: Authors: Dunford A, Weinstock DM, Savova V, Schumacher SE, Cleary JP, Yoda A, Sullivan TJ, Hess JM, Gimelbrant AA, Beroukhim R, Lawrence MS, Getz G, Lane AA.
Nat Genet
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Genes with monoallelic expression contribute disproportionately to genetic diversity in humans.
Authors: Authors: Savova V, Chun S, Sohail M, McCole RB, Witwicki R, Gai L, Lenz TL, Wu CT, Sunyaev SR, Gimelbrant AA.
Nat Genet
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dbMAE: the database of autosomal monoallelic expression.
Authors: Authors: Savova V, Patsenker J, Vigneau S, Gimelbrant AA.
Nucleic Acids Res
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Chromatin Signature Identifies Monoallelic Gene Expression Across Mammalian Cell Types.
Authors: Authors: Nag A, Vigneau S, Savova V, Zwemer LM, Gimelbrant AA.
G3 (Bethesda)
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Somatic Cell Fusions Reveal Extensive Heterogeneity in Basal-like Breast Cancer.
Authors: Authors: Su Y, Subedee A, Bloushtain-Qimron N, Savova V, Krzystanek M, Li L, Marusyk A, Tabassum DP, Zak A, Flacker MJ, Li M, Lin JJ, Sukumar S, Suzuki H, Long H, Szallasi Z, Gimelbrant A, Maruyama R, Polyak K.
Cell Rep
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