Jack Szostak headshot
Jack William Szostak, Ph.D.
Professor of Genetics
Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA.
Authors: Authors: Kim SC, O'Flaherty DK, Zhou L, Lelyveld VS, Szostak JW.
Proc Natl Acad Sci U S A
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A Kinetic Model of Nonenzymatic RNA Polymerization by Cytidine-5'-phosphoro-2-aminoimidazolide.
Authors: Authors: Walton T, Szostak JW.
Biochemistry
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Thiolated uridine substrates and templates improve the rate and fidelity of ribozyme-catalyzed RNA copying.
Authors: Authors: Prywes N, Michaels YS, Pal A, Oh SS, Szostak JW.
Chem Commun (Camb)
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Crystal structure studies of RNA duplexes containing s(2)U:A and s(2)U:U base pairs.
Authors: Authors: Sheng J, Larsen A, Heuberger BD, Blain JC, Szostak JW.
J Am Chem Soc
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Multicomponent assembly of proposed DNA precursors in water.
Authors: Authors: Powner MW, Zheng SL, Szostak JW.
J Am Chem Soc
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Expanding roles for diverse physical phenomena during the origin of life.
Authors: Authors: Budin I, Szostak JW.
Annu Rev Biophys
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Thermostability of model protocell membranes.
Authors: Authors: Mansy SS, Szostak JW.
Proc Natl Acad Sci U S A
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Ribosomal synthesis of dehydroalanine-containing peptides.
Authors: Authors: Seebeck FP, Szostak JW.
J Am Chem Soc
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A kinetic study of the growth of fatty acid vesicles.
Authors: Authors: Chen IA, Szostak JW.
Biophys J
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In vitro evolution suggests multiple origins for the hammerhead ribozyme.
Authors: Authors: Salehi-Ashtiani K, Szostak JW.
Nature
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