James Gusella headshot
James Francis Gusella, Ph.D.
Bullard Professor of Neurogenetics in the Department of Genetics
A rare exonic NRXN3 deletion segregating with neurodevelopmental and neuropsychiatric conditions in a three-generation Chinese family.
Authors: Authors: Yuan H, Wang Q, Liu Y, Yang W, He Y, Gusella JF, Song J, Shen Y.
Am J Med Genet B Neuropsychiatr Genet
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High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington's disease CAG knock-in mice across multiple genetic backgrounds.
Authors: Authors: Ament SA, Pearl JR, Grindeland A, St Claire J, Earls JC, Kovalenko M, Gillis T, Mysore J, Gusella JF, Lee JM, Kwak S, Howland D, Lee MY, Baxter D, Scherler K, Wang K, Geman D, Carroll JB, MacDonald ME, Carlson G, Wheeler VC, Price ND, Hood LE.
Hum Mol Genet
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CSF1R mosaicism in a family with hereditary diffuse leukoencephalopathy with spheroids.
Authors: Authors: Eichler FS, Li J, Guo Y, Caruso PA, Bjonnes AC, Pan J, Booker JK, Lane JM, Tare A, Vlasac I, Hakonarson H, Gusella JF, Zhang J, Keating BJ, Saxena R.
Brain
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Heritability of Risk for Sudden Cardiac Arrest in ESRD.
Authors: Authors: Chan KE, Newton-Cheh C, Gusella JF, Maddux FW.
J Am Soc Nephrol
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MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis.
Authors: Authors: Hoss AG, Kartha VK, Dong X, Latourelle JC, Dumitriu A, Hadzi TC, Macdonald ME, Gusella JF, Akbarian S, Chen JF, Weng Z, Myers RH.
PLoS Genet
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Clinical diagnosis by whole-genome sequencing of a prenatal sample.
Authors: Authors: Talkowski ME, Ordulu Z, Pillalamarri V, Benson CB, Blumenthal I, Connolly S, Hanscom C, Hussain N, Pereira S, Picker J, Rosenfeld JA, Shaffer LG, Wilkins-Haug LE, Gusella JF, Morton CC.
N Engl J Med
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Prevalence of Huntington's disease gene CAG repeat alleles in sporadic amyotrophic lateral sclerosis patients.
Authors: Authors: Ramos EM, Keagle P, Gillis T, Lowe P, Mysore JS, Leclerc AL, Ratti A, Ticozzi N, Gellera C, Gusella JF, Silani V, Alonso I, Brown RH, MacDonald ME, Landers JE.
Amyotroph Lateral Scler
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Intra-family phenotypic heterogeneity of 16p11.2 deletion carriers in a three-generation Chinese family.
Authors: Authors: Shen Y, Chen X, Wang L, Guo J, Shen J, An Y, Zhu H, Zhu Y, Xin R, Bao Y, Gusella JF, Zhang T, Wu BL.
Am J Med Genet B Neuropsychiatr Genet
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Changing models of biomedical research.
Authors: Authors: Crowley WF, Gusella JF.
Sci Transl Med
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Replication of association between ELAVL4 and Parkinson disease: the GenePD study.
Authors: Authors: DeStefano AL, Latourelle J, Lew MF, Suchowersky O, Klein C, Golbe LI, Mark MH, Growdon JH, Wooten GF, Watts R, Guttman M, Racette BA, Perlmutter JS, Marlor L, Shill HA, Singer C, Goldwurm S, Pezzoli G, Saint-Hilaire MH, Hendricks AE, Gower A, Williamson S, Nagle MW, Wilk JB, Massood T, Huskey KW, Baker KB, Itin I, Litvan I, Nicholson G, Corbett A, Nance M, Drasby E, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Al-Hinti J, Moller AT, Ostergaard K, Sherman SJ, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH.
Hum Genet
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