Stephen Elledge headshot
Stephen J. Elledge
Gregor Mendel Professor of Genetics and of Medicine
Genetic modifiers of the BRD4-NUT dependency of NUT midline carcinoma uncovers a synergism between BETis and CDK4/6is.
Authors: Authors: Liao S, Maertens O, Cichowski K, Elledge SJ.
Genes Dev
View full abstract on Pubmed
Systematic autoantigen analysis identifies a distinct subtype of scleroderma with coincident cancer.
Authors: Authors: Xu GJ, Shah AA, Li MZ, Xu Q, Rosen A, Casciola-Rosen L, Elledge SJ.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response.
Authors: Authors: Elia AE, Boardman AP, Wang DC, Huttlin EL, Everley RA, Dephoure N, Zhou C, Koren I, Gygi SP, Elledge SJ.
Mol Cell
View full abstract on Pubmed
Amphotericin B increases influenza A virus infection by preventing IFITM3-mediated restriction.
Authors: Authors: Lin TY, Chin CR, Everitt AR, Clare S, Perreira JM, Savidis G, Aker AM, John SP, Sarlah D, Carreira EM, Elledge SJ, Kellam P, Brass AL.
Cell Rep
View full abstract on Pubmed
Recurrent hemizygous deletions in cancers may optimize proliferative potential.
Authors: Authors: Solimini NL, Xu Q, Mermel CH, Liang AC, Schlabach MR, Luo J, Burrows AE, Anselmo AN, Bredemeyer AL, Li MZ, Beroukhim R, Meyerson M, Elledge SJ.
Science
View full abstract on Pubmed
The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo.
Authors: Authors: Meerbrey KL, Hu G, Kessler JD, Roarty K, Li MZ, Fang JE, Herschkowitz JI, Burrows AE, Ciccia A, Sun T, Schmitt EM, Bernardi RJ, Fu X, Bland CS, Cooper TA, Schiff R, Rosen JM, Westbrook TF, Elledge SJ.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart.
Authors: Authors: Ciccia A, Bredemeyer AL, Sowa ME, Terret ME, Jallepalli PV, Harper JW, Elledge SJ.
Genes Dev
View full abstract on Pubmed
Identification of MSA1, a cell cycle-regulated, dosage suppressor of drc1/sld2 and dpb11 mutants.
Authors: Authors: Li JM, Tetzlaff MT, Elledge SJ.
Cell Cycle
View full abstract on Pubmed
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response.
Authors: Authors: Wang B, Matsuoka S, Ballif BA, Zhang D, Smogorzewska A, Gygi SP, Elledge SJ.
Science
View full abstract on Pubmed
An open letter to cancer researchers.
Authors: Authors: Elledge SJ, Hannon GJ.
Science
View full abstract on Pubmed