Stephen Elledge headshot
Stephen J. Elledge
Gregor Mendel Professor of Genetics and of Medicine
MAPK Pathway Suppression Unmasks Latent DNA Repair Defects and Confers a Chemical Synthetic Vulnerability in BRAF-, NRAS-, and NF1-Mutant Melanomas.
Authors: Authors: Maertens O, Kuzmickas R, Manchester HE, Emerson CE, Gavin AG, Guild CJ, Wong TC, De Raedt T, Bowman-Colin C, Hatchi E, Garraway LA, Flaherty KT, Pathania S, Elledge SJ, Cichowski K.
Cancer Discov
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Brief Report: Anti-RNPC-3 Antibodies As a Marker of Cancer-Associated Scleroderma.
Authors: Authors: Shah AA, Xu G, Rosen A, Hummers LK, Wigley FM, Elledge SJ, Casciola-Rosen L.
Arthritis Rheumatol
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The DNA Damage Response--Self-awareness for DNA: The 2015 Albert Lasker Basic Medical Research Award.
Authors: Authors: Elledge SJ.
JAMA
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GLTSCR2/PICT1 links mitochondrial stress and Myc signaling.
Authors: Authors: Yoon JC, Ling AJ, Isik M, Lee DY, Steinbaugh MJ, Sack LM, Boduch AN, Blackwell TK, Sinclair DA, Elledge SJ.
Proc Natl Acad Sci U S A
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Systematic identification of synergistic drug pairs targeting HIV.
Authors: Authors: Tan X, Hu L, Luquette LJ, Gao G, Liu Y, Qu H, Xi R, Lu ZJ, Park PJ, Elledge SJ.
Nat Biotechnol
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Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate.
Authors: Authors: Emanuele MJ, Ciccia A, Elia AE, Elledge SJ.
Proc Natl Acad Sci U S A
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Cell biology forum: Genome-wide view of mitosis.
Authors: Authors: Swedlow JR, Cotta-Ramusino C, Elledge SJ.
Nature
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CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation.
Authors: Authors: Mulligan P, Westbrook TF, Ottinger M, Pavlova N, Chang B, Macia E, Shi YJ, Barretina J, Liu J, Howley PM, Elledge SJ, Shi Y.
Mol Cell
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Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage.
Authors: Authors: Wang B, Elledge SJ.
Proc Natl Acad Sci U S A
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ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency.
Authors: Authors: Cao L, Kim S, Xiao C, Wang RH, Coumoul X, Wang X, Li WM, Xu XL, De Soto JA, Takai H, Mai S, Elledge SJ, Motoyama N, Deng CX.
EMBO J
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