Reflecting the breadth of the field itself, the Department of Genetics at Harvard Medical School houses a faculty working on diverse problems, using a variety of approaches and model organisms, and having a unified focus on the genome as an organizing principle for understanding biological phenomena.
The Epigenetics Initiative and Annual Symposium have become an integral part of the HMS epigenetics community, not only to bring investigators and labs closer together, but also to provide support in the form of seed and travel grants.
G1 cyclins link proliferation, pluripotency and Differentiation of embryonic stem cells. Lijun Liu, Wojciech Michowski, Hiroyuki Inuzuka, Kouhei Shimizu, Naoe Taira Nihira, Joel M. Chick, Na Li, Yan Geng, Alice Y. Meng, Alban Ordureau, Aleksandra Kołodziejczyk, Keith L. Ligon, Roderick T. Bronson, Kornelia Polyak, J. Wade Harper, Steven P. Gygi, Wenyi Wei & Piotr Sicinski. Nature Cell Biology, USA 2017 February 13. Abstract
Destabilization of B2 RNA by EZH2 Activates the Stress Response. Athanasios Zovoilis, Catherine Cifuentes-Rojas, Hsueh-Ping Chu, Alfredo J. Hernandez and Jeannie T. Lee. Cell, USA 2016 Dec 15. Abstract
Cysteine Sulfenylation Directs IRE-1 to Activate the SKN-1/Nrf2 Antioxidant Response. Hourihan JM, Moronetti Mazzeo LE, Fernández-Cárdenas LP, Blackwell TK. Mol Cell. Aug. 2016 Abstract