Constance Cepko

Constance Cepko, Ph.D.

Bullard Professor of Genetics and Neuroscience, Harvard Medical School

Professor of Ophthalmology, Massachusetts Eye and Ear Infirmary

Investigator, Howard Hughes Medical Institute

617-432-7618

Cepko Lab Website

Publications

AAV NRF2 gene therapy preserves retinal structure and function in rodent models of oxidative damage.

Authors: Authors: Gardner A, Wang S, Daniels A, Li D, Wu C, Lin L, Hong C, Zhao SR, Born RT, Kruczek K, Weist G, Real LB, Wicks J, Nayal M, Carter A, Ott C, Haurigot V, Cepko CL.
Mol Ther 2026-06-03
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AAV NRF2 gene therapy preserves retinal structure and function in rodent models of oxidative damage.

Authors: Authors: Gardner A, Wang S, Daniels A, Li D, Wu C, Lin L, Hong C, Zhao SR, Born RT, Kruczek K, Weist G, Barrio Real L, Wicks J, Nayal M, Carter A, Ott C, Haurigot V, Cepko CL.
Mol Ther 2026-06-03
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Neuronal overexpression of Nrf2 reduces dystrophic neurites in 5XFAD Alzheimer's disease model mice.

Authors: Authors: Sadleir KR, Gomez KP, Chandra S, Ley ML, Khatri AW, Guo J, Xue Y, Cepko CL, Vassar R.
Alzheimers Res Ther 2026-06-03
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Tbx genes influence early gene expression and photoreceptor patterning in the chick retina.

Authors: Authors: Ayten M, Joisher HNV, Prabhakara C, Cepko C.
Dev Biol 2026-05-01
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Humanized extracellular vesicles for efficient RNA delivery.

Authors: Authors: Ma X, Zhao SR, Cepko CL.
Proc Natl Acad Sci U S A 2026-04-14
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Neuronal overexpression of Nrf2 reduces dystrophic neurites in 5XFAD Alzheimer's disease model mice.

Authors: Authors: Sadleir KR, Gomez KP, Chandra S, Ley ML, Khatri AW, Guo J, Xue Y, Cepko CL, Vassar R.
bioRxiv 2026-03-18
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Massively parallel reporter assay for mapping gene-specific regulatory regions at single-nucleotide resolution.

Authors: Authors: Tulloch AJ, Delgado RN, Catta-Preta R, Cepko CL.
Elife 2026-02-25
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Scaling Up Sequential Stepwise DNA Displacement-Based Signal Exchange for Rapid Ultraplex Fluorescent Imaging in Cells and Tissues.

Authors: Authors: Chen Y, Delgado RN, Xu E, Cepko CL, Hong F.
J Am Chem Soc 2026-02-04
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A congenic C57BL/6J rd1 mouse model for retinal degeneration research.

Authors: Authors: Chandler LC, Gardner A, Cepko CL.
Exp Eye Res 2026-02-01
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Integration of in situ hybridization and scRNA-seq data provides a 2D topographical map of the developing retina across species.

Authors: Authors: Joisher HNV, Lee C, Prabhakara C, van der Weide I, Si Y, Lonfat N, Cepko C.
bioRxiv 2026-01-04
View full abstract on Pubmed