Brian Seed headshot

Brian Seed, Ph.D.

Professor of Genetics
617-726-5975
Seed Lab Website
Myelinated, synapsing cultures of murine spinal cord--validation as an in vitro model of the central nervous system.
Authors: Authors: Thomson CE, McCulloch M, Sorenson A, Barnett SC, Seed BV, Griffiths IR, McLaughlin M.
Eur J Neurosci
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Quantitation of autophagy by luciferase release assay.
Authors: Authors: Ketteler R, Seed B.
Autophagy
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A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein.
Authors: Authors: Schöbel S, Neumann S, Hertweck M, Dislich B, Kuhn PH, Kremmer E, Seed B, Baumeister R, Haass C, Lichtenthaler SF.
J Biol Chem
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Spinophilin and the immune synapse.
Authors: Authors: Seed B, Xavier R.
J Cell Biol
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A pathway sensor for genome-wide screens of intracellular proteolytic cleavage.
Authors: Authors: Ketteler R, Sun Z, Kovacs KF, He WW, Seed B.
Genome Biol
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Molecular and functional analysis of the antigen receptor of Art v 1-specific helper T lymphocytes.
Authors: Authors: Leb VM, Jahn-Schmid B, Schmetterer KG, Kueng HJ, Haiderer D, Neunkirchner A, Fischer GF, Nissler K, Hartl A, Thalhamer J, Bohle B, Seed B, Pickl WF.
J Allergy Clin Immunol
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General strategy for decoration of enveloped viruses with functionally active lipid-modified cytokines.
Authors: Authors: Kueng HJ, Leb VM, Haiderer D, Raposo G, Thery C, Derdak SV, Schmetterer KG, Neunkirchner A, Sillaber C, Seed B, Pickl WF.
J Virol
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ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol.
Authors: Authors: Fitzgerald ML, Xavier R, Haley KJ, Welti R, Goss JL, Brown CE, Zhuang DZ, Bell SA, Lu N, McKee M, Seed B, Freeman MW.
J Lipid Res
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Direct stimulation of T lymphocytes by immunosomes: virus-like particles decorated with T cell receptor/CD3 ligands plus costimulatory molecules.
Authors: Authors: Derdak SV, Kueng HJ, Leb VM, Neunkirchner A, Schmetterer KG, Bielek E, Majdic O, Knapp W, Seed B, Pickl WF.
Proc Natl Acad Sci U S A
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A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies.
Authors: Authors: Kuo WP, Liu F, Trimarchi J, Punzo C, Lombardi M, Sarang J, Whipple ME, Maysuria M, Serikawa K, Lee SY, McCrann D, Kang J, Shearstone JR, Burke J, Park DJ, Wang X, Rector TL, Ricciardi-Castagnoli P, Perrin S, Choi S, Bumgarner R, Kim JH, Short GF, Freeman MW, Seed B, Jensen R, Church GM, Hovig E, Cepko CL, Park P, Ohno-Machado L, Jenssen TK.
Nat Biotechnol
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