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Commitment to Equity, Diversity, Inclusion, and Belonging
Harvard University views equity, diversity, inclusion, and belonging as the pathway to achieving inclusive excellence and fostering a campus culture where everyone can thrive. We strive to create a community that draws upon the widest possible pool of talent to unify excellence and diversity while fully embracing individuals from varied backgrounds, cultures, races, identities, life experiences, perspectives, beliefs, and values.
EEO Statement
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.
Vaccine requirement
The University requires all Harvard community members to be fully vaccinated against COVID-19 and remain up to date with COVID-19 vaccine boosters, as detailed in Harvard’s Vaccine & Booster Requirements. Individuals may claim exemption from the vaccine requirement for medical or religious reasons. More information regarding the University’s COVID vaccination requirement, exemptions, and verification of vaccination status may be found at the University’s “COVID-19 Vaccine Information” webpage: http://www.harvard.edu/coronavirus/covid-19-vaccine-information/.
Open Positions:
Postdoctoral Fellowship Position: Stem Cell Program in Carla Kim Lab
The Kim Lab in the Stem Cell Program at Boston Children’s Hospital seeks a highly motivated postdoctoral research fellow, who will conduct research under the mentorship of Dr. Carla Kim, Professor of Genetics at Harvard Medical School, Harvard Stem Cell Institute Faculty Member, and Member of the Stem Cell Program at Boston Children’s Hospital.
The broad interest of the Kim Lab is to use stem cell biology to increase our understanding of how mechanisms governing normal lung biology are impacted in lung disease and lung cancer. Our lab utilizes co-culture organoid systems that allow us to define how mouse and human lung epithelial progenitor cells are regulated by cell-cell communication. Multiple projects are aimed
at using these systems to shed light on lung cancer, emphysema, COPD, idiopathic pulmonary fibrosis and other lung diseases. The position offers an exciting opportunity to work closely with scientists and medical professionals in the highly collaborative and stimulating environment of the Stem Cell Program at Boston Children’s Hospital located in the vibrant Longwood / Harvard
Medical Area.
There are several projects in the Kim lab for postdoctoral research fellows, including but not limited to:
- Transplantation of lung organoids to repair damaged lungs. The Kim lab is exploring the transplantation of healthy lung organoids as a tool for understanding lung stem cell biology and as a possible means to future cell-based therapy in diseased lungs.
- Organoid models of early stage lung cancer. We are using lung organoids that carry tumorigenic mutations to model the early steps of lung adenocarcinoma and devise new strategies to impair the progression of small lesions to full malignant growth.
Recent Kim Lab publications:
Progenitor potential of lung epithelial organoid cells in a transplantation model. Louie SM, Moye AL, Wong IG, Lu E, Shehaj A, Garcia-de-Alba C, Ararat E, Raby BA, Lu B, Paschini M, Bronson RT, Kim CF. Cell Rep. 2022 Apr 12;39(2):110662. doi: 10.1016/j.celrep.2022.110662.
Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial
Progenitor Cells.
Dost AFM, Moye AL, Vedaie M, Tran LM, Fung E, Heinze D, Villacorta-Martin C, Huang J,
Hekman R, Kwan JH, Blum BC, Louie SM, Rowbotham SP, Sainz de Aja J, Piper ME, Bhetariya PJ,
Bronson RT, Emili A, Mostoslavsky G, Fishbein GA, Wallace WD, Krysan K, Dubinett SM,
Yanagawa J, Kotton DN, Kim CF.
Cell Stem Cell. 2020 Oct 1;27(4):663-678.e8. doi: 10.1016/j.stem.2020.07.022. Epub 2020 Sep 4.
BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency. Gupta M, Concepcion CP, Fahey CG, Keshishian H, Bhutkar A, Brainson CF, Sanchez-Rivera FJ, Pessina P, Kim JY, Simoneau A, Paschini M, Beytagh MC, Stanclift CR, Schenone M, Mani DR, Li C, Oh A, Li F, Hu H, Karatza A, Bronson RT, Shaw AT, Hata AN, Wong KK, Zou L, Carr SA, Jacks T, Kim CF.
Cancer Res. 2020 Sep 15;80(18):3841-3854. doi: 10.1158/0008-5472.CAN-20-1744. Epub 2020 Jul 20.
Requirements:
The candidate should have a Ph.D. or an M.D./Ph.D. No postdoctoral experience is required.
How to apply:
Interested applicants should email their CV, a cover letter indicating research experience, interests and goals, and names/contact information for at least three academic references to the Dr. Carla Kim at Carla.Kim@childrens.harvard.edu.
Postdoctoral Fellow – Engineered Cell-Based Therapeutics
About the Wyss:
The mission of the Wyss Institute for Biologically Inspired Engineering at Harvard University is to transform human healthcare and the environment by emulating the way nature builds. Developed as an alliance between Harvard and other premier academic and clinical partner institutions, Institute faculty and staff collaborate in high-risk, fundamental research and science-driven technology development. A major focus of the Institute is to translate the technologies developed by its faculty and staff into commercial products and therapies through collaborations with clinical investigators and establishment of corporate alliances. For more information, discover our technologies, catch up on our recent news, or watch our latest videos.
Role Description:
The laboratory of Dr. George Church at the Wyss Institute at Harvard Medical School in Boston, MA is looking for a Postdoctoral Fellow to join our rapidly growing team, interested in engineering immune cells to overcome unmet needs in cell therapy. To this end, we have developed a pipeline leveraging DNA barcoding & next-generation-sequencing to perform in-vivo pooled discovery for complex cellular behaviors such as cellular trafficking.
We are looking for a passionate, impact-motivated scientist and problem solver who relishes the opportunity to participate in fast-paced, dynamic research. Candidates should be focused on delivering impact through translational science, enjoy working with diverse groups of people, and leverage their expertise to create impactful innovations.
The Postdoctoral Fellow will have the opportunity to lead projects within the Wyss Institute’s SomaCode team focused on in vivo discovery. Research will be performed in an interdisciplinary manner within the Wyss Institute and with collaborators in the Harvard Medical School community. We are particularly interested in scientists with strong wet lab experience in immune cell engineering, cancer biology, or library design. Working alongside the project leads, you will assist in key research studies involving in-vivo pooled functional genomics of immune cells for applications in the oncology and autoimmune spaces. Additionally, you will be closely involved in the continued development of our in-vivo pooled screening platform and related technologies.
As a Northpond Labs supported project, the postdoctoral fellow will also have opportunities relating to early-stage innovation and commercialization for which the Church lab has a history of effectively translating novel technology concepts into new biotech startups focused on addressing unmet needs for patients living with debilitating diseases. In addition to professional development opportunities within the lab and exposure to a breadth of scientific disciplines, the Postdoctoral Fellow will be able to take advantage of the scientific communities within Harvard, the Wyss Institute, and the greater Boston area.
What You’ll Need:
- Ph.D. or equivalent
- Specific degree areas include but are not limited to immunology, oncology, synthetic biology, functional genomics, and molecular biology.
Preferred:
Preferably, applicants should be able to:
- Independently plan, design, and execute on in-vivo experiments relating to our pooled screening platform in human and murine T cells
- Design, clone, confirm and implement new libraries, strategies for library generation, and assist in the continued development of our robust screening platform
- Help manage and mentor our team of graduate students, research assistants, and undergraduate researchers
- Initiate, maintain, and execute on both industry and academic collaborations relating to the application of our platform across diverse cell types and disease spaces
- Accurately and thoroughly document experimental observations and protocols and help maintain a high level of organizational efficiency within the lab
- Demonstrate a commitment to diversity, inclusion, and cultural awareness in the workplace through actions & communications with others
- Prior experience with primary human/murine immune cell isolation, culture, and modification is advantageous, but not required
- Prior experience with in-vivo murine work is desired
- Familiarity with python, R or similar programming language is advantageous, but not required
- Highly effective organizational and communication skills are essential
Benefits and Perks:
- Medical/Dental/Vision: We offer a variety of excellent medical, dental, & vision plans. All coverage begins as of your start date.
- Time Off: 20 days of vacation per year
- Tuition Assistance Program: Competitive tuition assistance program, classes at the Harvard Extension School and discounted options through participating Harvard grad schools.
- Transportation: Harvard offers a 50% discounted MBTA pass as well as additional options to assist employees in their daily commute.
- Wellness Options: Harvard offers programs and classes at little or no cost, including stress management, nutrition, meditation, and complimentary health services.
Where You Can Apply:
Applications, assembled as single PDF files, should contain a complete resume, cover letter describing research interests and goals, full list of publications, copies of up to three relevant scientific papers, as well as the names and contact information of three references (expected to provide letters of recommendation). Applications should be sent to faculty_postdocs@wyss.harvard.edu using the subject line “ENGINEERED CELL-BASED THERAPEUTICS APPLICATION.”
Working Conditions
Harvard requires COVID vaccination for all Harvard community members. Individuals may claim exemption from the vaccine requirement for medical or religious reasons. More information regarding the University’s COVID vaccination requirement, exemptions, and verification of vaccination status may be found at the University’s “COVID-19 Vaccine Information” webpage: http://www.harvard.edu/coronavirus/covid-19-vaccine-information/.
Senior Research Portfolio Administrator
Job Summary
The mission of the Department of Genetics at the Harvard Medical School encompasses research and education while serving as a focal point for drawing together and integrating basic and clinical genetic efforts conducted across the University, the School, and HMS-affiliated hospitals. The scope of the work conducted includes but is not limited to human genetics of both single gene disorders and complex traits, development of genomic technology, cancer biology, developmental biology, signal transduction, cell biological problems, stem cell biology, computational genetics, immunology, synthetic biology, epigenetics, evolutionary biology, and plant biology. The Department is strongly committed to supporting its current community of faculty, postdoctoral fellows, and graduate students, securing the best up-and-coming scientists, and setting its sights on future research opportunities.
Research Portfolio Administration is integral to the department's success. Research Portfolio Administrators oversee the administration, management, and reporting of research funds devoted to innovative genetic studies to unravel human biology's complexities. They coordinate grant proposals, manage budgets, ensure compliance with funding guidelines, and foster collaborative relationships with principal investigators, postdoctoral researchers, and graduate students. They are vital in advancing groundbreaking genetics research with the highly regarded faculty in a collaborative environment that offers a unique opportunity to develop and hone critical thinking, financial analysis, and communication skills while supporting the academic mission of Harvard Medical School.
Position Description
Areas of accountability in Research Portfolio Administration within Genetics include but are not limited to:
Pre-Award responsibilities:
- Managing the application process with researchers, subrecipient institutions, and other administrators to meet internal and external deadlines.
- Working with PIs to prepare and submit grant applications for basic and clinical research (if applicable), ensuring that all sponsor guidelines are met.
- Advising researchers on funding opportunity requirements and fiscal, administrative, and compliance policies and procedures.
- Preparation of project-specific budgets, including proper application of F&A costs.
- Entering proposals into Harvard’s system of record (GMAS) and sponsor portals (e.g., ASSIST, Grants.gov Workspace, Research.gov, Proposal Central) and routing to ORA for institutional review, authorization, and submission.
- Drafting timely responses to Just-In-Time requests, including revised budgets, current and pending support, and compliance approvals (e.g., IRB, IACUC) information.
Post-Award responsibilities:
- Daily monitoring of grants and contracts for PIs assigned to a department portfolio.
- Serving as the principal source of information on complex fiscal policies and procedures, including federal funding regulations, and advising faculty and staff on existing options or alternatives.
- Post-award management with a high degree of complexity; manages portfolio, including program projects, philanthropic gifts, and various domestic and international sub-agreements from federal and non-federal funding sources, ensuring compliance with federal and university cost principles.
- Understanding and applying award terms and conditions, regularly reviewing study progress, and generating accurate and timely invoices to sponsors.
- Monitoring sponsored award expenditures to ensure that expenses are properly charged and reimbursed, according to award terms and conditions and within budget limits and timelines.
- Managing oversight of subrecipients, including ongoing monitoring of spending and of special terms and conditions.
- Preparing financial projection reports to analyze spending patterns and rates. Notifying PIs about funding shortfalls and planning for contingencies.
- Reviewing and approving payments, including vendor invoices, individual reimbursements, and other accounts payables and receivables.
- Submitting timely payroll changes for faculty and staff.
- Maintaining accurate records of personnel effort and corresponding salary charges to sponsored awards and assisting faculty and staff with quarterly and annual effort certifications.
- Preparing progress reports and prior approval requests and routing them for institutional review, authorization, and submission to sponsors.
- Interpret and administer university guidelines and sponsored research regulations; provide guidance to faculty about department, university, and sponsored policies.
- Working with OSP to close out sponsored projects per award requirements.
If you have a passion for genetics research, a desire to lend your exceptional organizational skills, and a knack for financial management toward improving human health, we invite you to join our team! Take this unique opportunity to contribute to unraveling human biology's complexities while developing your skills in a collaborative and supportive environment.
Basic Qualifications
Five or more years of experience in sponsored research administration or related experience required. Higher education may count toward years of experience.
For details regarding department and role-specific Basic Qualifications, visit our department webpage at:
https://genetics.hms.harvard.edu/about-us/departmental-employment-opportunities
Additional Qualifications and Skills
- Demonstrated knowledge of federal Uniform Guidance, NIHGPS, NSF PAPPG, and current issues in research administration.
- Experience using ASSIST, eRA Commons, Research.gov, Grants.gov Workspace, and other sponsor systems.
- Proven ability to work collaboratively and independently in managing multiple projects in a fast-paced, deadline-driven environment.
- Must possess excellent written and verbal communication skills.
- Solid computer skills such as proficiency with Microsoft Office; intermediate to advanced Excel skills required.
- Demonstrated knowledge of financial principles, budget management, and financial analysis.
- Experience and working knowledge with clinical trials for the full span of an award preferred (if applicable).
Additional Information
The health of our workforce is a priority for Harvard University. With that in mind, we strongly encourage all employees to be up-to-date on CDC-recommended vaccines.
Please note that we are currently conducting a majority of interviews and onboarding remotely and virtually. We appreciate your understanding.
The Harvard Medical School is not able to provide visa sponsorship for this position.
Not ready to apply? Join our talent community to keep in touch and learn about future opportunities! (https://www.gem.com ?formID=16341e35-cbc6-4904-88a3-09b35763307e)
Work Format Details
This is a hybrid position that is based in Massachusetts. Additional details will be discussed during the interview process. All remote work must be performed within one of the Harvard Registered Payroll States, which currently includes Massachusetts, Connecticut, Maine, New Hampshire, Rhode Island, Vermont, Georgia, Illinois, Maryland, New Jersey, New York, Virginia, Washington, and California (CA for exempt positions only). Certain visa types and funding sources may limit work location. Individuals must meet work location sponsorship requirements prior to employment.
More information here.
Researcher II/Lab Manager in Church Lab
Job-Specific Responsibilities
Department of Genetics, Harvard Medical School, Wyss Institute
The Church Lab invites applications for an immediate opening for a Research Scientist/Lab Manager.
Our research focuses on new technologies for genomic & proteomic measurement, synthesis and modeling of biomedical & ecological systems -- in particular, personal genomics and biofuels. We have developed next-generation sequencing methods to analyze the output of combinatorial selections as well as comprehensive gene-environment-trait data for affordable personalized medicine. We reprogram human skin-derived pluripotent skin cells to connect cis-regulatory motif variants in populations to allele-specific and cell-type-specific RNA measures and further to causal effects on cell and larger-scale morphologies. We are developing tools for connecting functional microbiomics with (VDJ-ome) immune responses.
This position will have responsibility for daily research operations of leading a biomedical research laboratory in the Harvard Medical School Department of Genetics. Additionally, the individual will be responsible for the experimental design and execution of research projects relating to the work in the Church lab, which includes helping to provide research guidance to members of the research lab. Will assist lab members with obtaining required approvals for research involving biohazards, animals (IACUC), or human subjects (IRB). May help prepare scientific progress reports and grant proposals. This position will also be responsible for ensuring adherence to all appropriate safety regulations and performing and tracking safety training of lab members. Additional duties will include the implementation of HMS, Department and Lab policies which include data management, MTAs and other lab compliance responsibilities. Other duties may include managing weekly lab supply inventory, allocating/purchasing as needed, and serving as first-line approver of purchase requests.
Basic Qualifications
Bachelor's degree required. Three + years of progressively responsible research/lab management, ideally in a biomedical/life sciences laboratory.
Additional Qualifications and Skills
PhD preferred
• Experience with safety regulations and requirements in the areas of Biosafety, Radiation, and Chemical/Waste.
• Familiarity with writing grant applications and reports.
• Experience creating and administering lab systems, practices, policies, and procedures.
• Operational knowledge of advanced lab equipment.
• Experience with Microsoft Word and Excel.
• Must be organized, dependable, and possess good problem-solving skills.
• Ability to work independently as well as oversee a team of researchers in conjunction with PI.
• Ability to work well with others in a collaborative team environment.
• Strong communication skills and a positive attitude.
• Strong initiative and the ability to self-start are essential.
• Ability to think creatively about functional improvements for how the lab operates and implement improvements as appropriate.
• Ability to lift, move, and transport research related equipment up to 10 pounds required.
Special Instructions
A complete application must include an updated CV, a cover letter, and a research statement. In the research statement please address your experience with lab operations such as overseeing lab safety regulations, animal research protocols, advanced lab equipment, and training lab personnel. Please submit the names and contact information for three references.
We strongly encourage applications from members of underrepresented groups.
Additional Information
This is a 1-year term position with strong possibility of extension, contingent on work performance and continued funding to support the position.
Offer contingent on successful completion of pre-placement medical evaluation.
Harvard will require COVID vaccination for all Harvard community members who will have any on-campus presence. Individuals may claim exemption from the vaccine requirement for medical or religious reasons. More information regarding the University’s COVID vaccination requirement and exceptions may be found at the University’s “COVID-19 Vaccine Information” webpage: http://www.harvard.edu/coronavirus/covid-19-vaccine-information/.
Please note that we are currently conducting a majority of interviews and onboarding remotely and virtually. We appreciate your understanding.
We are committed to cultivating an inclusive workplace culture of faculty, staff, and students with diverse backgrounds, styles, abilities, and motivations. We appreciate and leverage the capabilities, insights, and ideas of all individuals. Harvard Medical School Mission and Community Values
More information and application here
Researcher II/Lab Manager in Church Lab
Job-Specific Responsibilities
Department of Genetics, Harvard Medical School, Wyss Institute
The Church Lab invites applications for an immediate opening for a Research Scientist/Lab Manager.
Our research focuses on new technologies for genomic & proteomic measurement, synthesis and modeling of biomedical & ecological systems -- in particular, personal genomics and biofuels. We have developed next-generation sequencing methods to analyze the output of combinatorial selections as well as comprehensive gene-environment-trait data for affordable personalized medicine. We reprogram human skin-derived pluripotent skin cells to connect cis-regulatory motif variants in populations to allele-specific and cell-type-specific RNA measures and further to causal effects on cell and larger-scale morphologies. We are developing tools for connecting functional microbiomics with (VDJ-ome) immune responses.
This position will have responsibility for daily research operations of leading a biomedical research laboratory in the Harvard Medical School Department of Genetics. Additionally, the individual will be responsible for the experimental design and execution of research projects relating to the work in the Church lab, which includes helping to provide research guidance to members of the research lab. Will assist lab members with obtaining required approvals for research involving biohazards, animals (IACUC), or human subjects (IRB). May help prepare scientific progress reports and grant proposals. This position will also be responsible for ensuring adherence to all appropriate safety regulations and performing and tracking safety training of lab members. Additional duties will include the implementation of HMS, Department and Lab policies which include data management, MTAs and other lab compliance responsibilities. Other duties may include managing weekly lab supply inventory, allocating/purchasing as needed, and serving as first-line approver of purchase requests.
Basic Qualifications
Bachelor's degree required. Three + years of progressively responsible research/lab management, ideally in a biomedical/life sciences laboratory.
Additional Qualifications and Skills
PhD preferred
• Experience with safety regulations and requirements in the areas of Biosafety, Radiation, and Chemical/Waste.
• Familiarity with writing grant applications and reports.
• Experience creating and administering lab systems, practices, policies, and procedures.
• Operational knowledge of advanced lab equipment.
• Experience with Microsoft Word and Excel.
• Must be organized, dependable, and possess good problem-solving skills.
• Ability to work independently as well as oversee a team of researchers in conjunction with PI.
• Ability to work well with others in a collaborative team environment.
• Strong communication skills and a positive attitude.
• Strong initiative and the ability to self-start are essential.
• Ability to think creatively about functional improvements for how the lab operates and implement improvements as appropriate.
• Ability to lift, move, and transport research related equipment up to 10 pounds required.
Special Instructions
A complete application must include an updated CV, a cover letter, and a research statement. In the research statement please address your experience with lab operations such as overseeing lab safety regulations, animal research protocols, advanced lab equipment, and training lab personnel. Please submit the names and contact information for three references.
We strongly encourage applications from members of underrepresented groups.
Additional Information
This is a 1-year term position with strong possibility of extension, contingent on work performance and continued funding to support the position.
Offer contingent on successful completion of pre-placement medical evaluation.
Harvard will require COVID vaccination for all Harvard community members who will have any on-campus presence. Individuals may claim exemption from the vaccine requirement for medical or religious reasons. More information regarding the University’s COVID vaccination requirement and exceptions may be found at the University’s “COVID-19 Vaccine Information” webpage: http://www.harvard.edu/coronavirus/covid-19-vaccine-information/.
Please note that we are currently conducting a majority of interviews and onboarding remotely and virtually. We appreciate your understanding.
We are committed to cultivating an inclusive workplace culture of faculty, staff, and students with diverse backgrounds, styles, abilities, and motivations. We appreciate and leverage the capabilities, insights, and ideas of all individuals. Harvard Medical School Mission and Community Values
More information and application here
Postdoctoral Position as Image Analyst for Spatial Genomics
We are seeking computational experts to join the laboratory of Ting Wu (Harvard Medical School) in their CEGS (NIH/NHGRI) journey to image, analyze, and model the human genome at super-resolution. Individuals with extensive computational experience as well as a penchant for innovating and applying tools at all levels of imaging (from high throughput feature extraction and image processing to image analysis and modeling) are encouraged to apply. A strong sense of collaboration and high levels of self-motivation, creativity, and open-mindedness will be appreciated. Experience in machine learning will be advantageous. Candidates can anticipate joining an interdisciplinary team of geneticists, microscopists, chemists, engineers, physicists, and computational experts. We are excited to meet you at the interface of computation, experimentation, and theory.
Qualifications:
• Expertise in Computational Biology, Data Science, Statistics, and/or related fields.
• Proficiency in Python, R, and cloud/cluster computing.
• Familiarity with Machine Learning, Neural Networks, and/or Artificial Intelligence for building, testing, and evaluating predictive and classification models.
• Strong presentation and communication skills both verbal and written. For immediate consideration, please submit your cover letter and resume to Sarah Aufmkolk, Ph.D. (Sarah_Aufmkolk(at)hms(dot)harvard(dot)edu.
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.
Disclaimer: Harvard will require COVID vaccination for all Harvard community members who will have any on-campus presence. Individuals may claim exemption
from the vaccine requirement for medical or religious reasons. More information regarding the University’s COVID vaccination requirement and exceptions may be
found at the University’s “COVID-19 Vaccine Information” webpage: http://www.harvard.edu/coronavirus/covid-19-vaccine-information/
Multiple PhD Positions at the Dana Farber Center for Protein Degradation
Please find information about the center here: https://cpd.dana-farber.org/
And information on the positions here:https://careers.dana-farber.org/job/biology-scientist-center-for-protein-degradation-research-technician-scientist-boston-ma-23933/
You can also email your CV directly to Nikki Kong: