We encourage you to visit the school-wide Jobs@HMS page. 


Research Cores and Technology Program Coordinator
Harvard Medical School

Job-Specific Responsibilities

The Harvard Medical School research core facilities and technology platforms provide access to highly specialized services, equipment, and staff that would otherwise be too expensive for an individual laboratory to support. The Associate Dean for Research Cores and Technology and her team, as part of the Office for Research Operations, support research infrastructure and access to new technologies by providing central coordination, funding, and administrative resources for HMS core facilities, platforms, and technology development projects.

The Research Cores and Technology Coordinator performs a wide range of highly skilled administrative duties for the Associate Dean for Research Cores and Technology. The Coordinator:

  • Manages complex calendars, arranges for meetings, appointments, and travel for business trips.
  • Organizes and staffs a range of committee meetings, programs, events, and symposia relevant to research core activities at Harvard Medical School and affiliated institutions.
  • Assists in developing websites for new projects and provides general maintenance for existing websites.
  • Works as part of a team helping to implement and maintain the HMS cores management system, and to run reports from it.
  • Assists with administration of the HMS Foundry Awards program, which provides funding for research cores and other HMS shared research resource projects.
  • Assists with meeting preparation including printing out necessary meeting materials, identifying meeting location and time, arranging transportation/parking, and ordering catering, as needed.
  • Provides a wide range of clerical support including composing and editing letters, memoranda, reports, and presentations. Serves as the principal administrative contact for visitors.
  • Prepares and produces financial reports using online financial systems, such as reimbursement for travel, corporate cards, HU purchasing cards, etc.
  • Handles other administrative and operational needs for the Associate Dean, as needed.

The Research Cores and Technology Coordinator will work effectively within a culture inclusive of individuals with diverse backgrounds, styles, abilities, and motivations, and appreciate and leverage the capabilities, insights, and ideas of all individuals.

Basic Qualifications
At least 3 years of experience in administration or laboratory management.

Additional Qualifications and Skills
Bachelor’s Degree preferred. Strong verbal and written skills, with the ability to summarize complex discussions. Ability to multitask. Solid working knowledge of office processes and systems, and of related computer software and electronic communications tools. Strong interest in the biomedical sciences and in learning more about support for research infrastructure.

Apply Here


Woolly Mammoth Revival Fellowship Announcement

Description of the Opportunity

Revive & Restore is pleased to announce a post-doctoral fellowship opportunity for well-qualified individuals interested in a full-time appointment researching the science underlying Woolly Mammoth de-extinction in the laboratory of Dr. George Church at Harvard Medical School. This fellowship is fully supported by Revive & Restore, the leading non-profit organization working to bring biotechnologies to wildlife conservation. The fellowship will include the following benefits:

  • 1-year renewable post-doctoral fellowship
  • Harvard Medical School will serve as the host institution and administer the fellowship
  • $75,000 annual gross salary and stipendee postdoc benefits
  • $25,000 per year for research materials and access to complementary Promega supplies
  • Revive & Restore sponsorship and project management
  • The opportunity to conduct pioneering work on de-extinction technology

Eligibility Requirements

  • Eligible applicants must have a PhD in molecular biology, genetics, biochemistry, or related discipline;
  • Less than 2 years prior post-doctoral experience;
  • Expertise in cell culture, stem cells, gene editing techniques, and/or mammalian developmental biology;
  • Be creative, self-driven, organized, a clear communicator, and possess excellent time management skills;
  • Demonstrated ability to work towards specific milestones and goals;
  • An interest in genetic rescue applications of biotechnology

Background Information

The tundra and much of the taiga were once a grassland ecosystem known as the “mammoth steppe.” It was home to abundant grazing herds of Woolly Mammoths, antelope, deer, caribou, horses, and bison. At the end of the Pleistocene these herds vanished leading to an ecosystem conversion away from abundant grasses toward a more shrub dominated community.

The tundra ecosystem that arose in the absence of these large grazing species is now affected by and contributing to human-driven climate change. Without large animals to compact and scrape away thick insulating layers of winter snow, extreme winter cold does not penetrate the soil. That fact, coupled with significantly warmer summers, accelerates the melting of the permafrost and the release of greenhouse gases that have been trapped for millennia.  From a global carbon perspective, the carbon release from melting of the world’s permafrost is equivalent to burning all the world’s forests 2 ½ times.

The work of Dr. Sergey Zimov shows that tundra can be converted back to grasslands with the introduction of grazers even 10,000 years after their disappearance. The introduction of grazers to tundra generates a nutrient cycle that allows grasses to out-compete the tundra flora, converting the ecosystem in a manner that then favors the persistence of grazers and grasses. Not only do arctic grasslands support higher biodiversity and abundance, there is evidence that the grazing, compaction and disturbance effects of these larger herbivores enables the deeper freezing of the permafrost during the winter months.  The grasses then insulate the permafrost from melting during summer months – further preventing the release of greenhouse gases.

Research suggests grasslands sequester carbon from the atmosphere more efficiently than other ecosystems. The grazing cycle’s multi-dimensional climate dynamics offers a potentially powerful tool for fostering resilience in the face of human-driven climate change.

Breakthrough advances in genomic biotechnology are presenting the possibility of bringing back long-extinct species — or at least “proxy” species with traits and ecological functions similar to the extinct originals.

The Woolly Mammoth has emerged as a leading candidate for this work. It can be attempted because a close relative of the mammoth is still living—the Asian elephant. Thanks to the similarity of their genomes, the genes of woolly mammoth traits can be edited into the Asian elephant genome, and the combination brought to life as an elephant cousin, once again adapted to the conditions of the far north.

The ultimate goal of Woolly Mammoth Revival is to bring back this extinct species so that healthy herds may one-day re-populate vast tracts of tundra and boreal forest in Eurasia and North America. The intent is not to make perfect copies of extinct Woolly Mammoths, but to focus on the mammoth adaptations needed for Asian elephants to thrive in the cold climate of the Arctic. The milestones along the way range from developing elephant tissue cultures to genome editing and most importantly, developing insights that help with Asian elephant conservation.

The Woolly Mammoth Revival team headed by George Church is working to identify cold climate adapted alleles of the mammoth genome and edit them into living elephant cells. From there, the team will study the expression of Woolly Mammoth mutations to test predictions about gene function. Specifically, how does evolution shape the same gene to be adapted to tropical habitats in one lineage, while adapting an alternate version of that gene to cold habitats? Not only does this research build the foundations of mammoth de-extinction, it provides potentially valuable insight to evolution for different climate conditions. These insights may demonstrate techniques to apply genetic biotechnologies to facilitate adaptation for wildlife threatened by climate change.

Application Process

Interested applicants should send a cover letter, CV, and contact information for three professional references to Revive & Restore (bridget AT reviverestore.org). Applications will be reviewed on a rolling basis until a qualified candidate is selected. An initial review will be conducted based on past research experience and overall fit. Additional information on Mammoth project specifics will be provided by Dr. Church to applicants that pass the first round of screening. Finalists will be asked to develop a 1-yr project plan for first year of fellowship with guidance from Revive & Restore. Fellow(s) will be selected based on project plan approval by Revive & Restore and Dr. Church. The fellowship can be iteratively renewed at the end of each year for up to 3 years.


Post-doctoral (Ph.D.) position available (Sinclair Lab)

We are seeking a talented, highly motivated researcher to join the laboratory of Professor David Sinclair in the Genetics Department at Harvard Medical School, Boston. The Sinclair lab is known for their work on genes and small molecules that delay or reverse aging. They have identified a new approach to safely reverse the age of tissues and used it to restore the vision of old mice, a study that was recently on the cover of Nature. The lab has a wide range of expertise and interests, including cancer, neurodegeneration, blindness, diabetes, and muscle degeneration.

The position offers an opportunity to work with an engaged group of scientists and participate in cutting-edge research funded by NIH and various private foundations. The ideal candidate will have hands on experience with genetics and genomics, molecular and cellular biology techniques, epigenetics, and small animal husbandry. The candidate will work to understand and utilize epigenetic reprogramming to safely reverse aging and treat both rare and common diseases. This will include both the use of existing approaches and the development of new ones.

Required Skills/Abilities/Competencies:

  • A Ph.D. in genetics, molecular biology, biochemistry, genomics, systems biology, or related.
  • Strong scientific knowledge of molecular and cellular biology, genetics and epigenetics.
  • Experience with small animal husbandry.
  • Outstanding personal initiative and creativity.
  • Ability to interpret complex data sets and design subsequent experiments.
  • Excellent teamwork, time management and organizational skills.
  • Ability to work independently in a multidisciplinary, fast-paced, results-oriented environment.
  • Talent in presenting data to a multidisciplinary audience in a clear and cohesive manner.
  • Ability to meet deadlines and multitask efficiently is a must.

The ideal candidate will have a record of scientific rigor and creativity, a strong publication record in peer-reviewed scientific journals and the ability to work in teams. Excellent oral and written communication skills are required. The individual will present regular updates to academic and industry collaborators as well as prepare and publish research reports. There is a real opportunity to invent and to innovate.

To apply, send cover letter and CV to luis_rajman@hms.harvard.edu


Research Assistant I - Kim Lab

56970BR

Medicine-Hematology/Oncology

Job Posting Description

The Stem Cell Program at Boston Children's Hospital seeks applications from highly motivated candidates for the position of Research Assistant I in the Carla Kim Laboratory, which is focused on the study of lung stem cell biology, regenerative medicine and lung cancer research. Candidate will have the opportunity to support multiple research projects and will conduct a variety of techniques such as DNA/RNA isolation, PCR, immunohistochemistry, molecular cloning, tissue culture and other molecular biology techniques. This is an excellent transition opportunity for a recent college graduate interested in pursuing further graduate or medical education after 2 years. Previous Kim lab assistants have been co-authors on several papers and are now enrolled in highly competitive medical and graduate school programs.
 
This Research Assistant I will be responsible for: 

  • Under immediate supervision, performs a variety of routine and specialized laboratory experimental, specimen preparations and experimental procedures for the purpose of research. Assists in the use of specialized laboratory equipment and analysis of data generated by this equipment
  • According to prescribed protocols and assigned schedules, performs a variety of routine laboratory experiments and procedures, utilizing standard laboratory equipment, recording and checking results for completeness and accuracy.
  • Assists in troubleshooting procedures if experimental results are unexpected or quality of specimens is poor.
  • Performs the following techniques typically required for the laboratory/study:
    • Maintains records of results and methodologies in a log of work performed.
    • Maintains equipment, lab area and supplies in a neat professional manner.
    • Sterilize and clean glassware, prepare media and other materials using appropriate procedures.
    • Inventories supplies alerts supervisor to needed supplies, or mixes standard reagents.
    • Processes order for supplies and/or animals. Attends courses in safety procedures for handling, storage and disposal of biohazardous, flammable, corrosive and toxic materials.
    • Carries out all laboratory activities in compliance with applicable regulations and protocols.
  • Conducts literature searches and reviews, compiling information for journals and suggesting uses for new techniques to the P.I.
  • Attends courses, lectures and conferences to further own knowledge of research and laboratory techniques, consulting with other researchers and technicians to exchange information.
  • Contributes to the team within and between departments and organizations.


To qualify, you must have:

  • The knowledge of theories, principles, and concepts acquired through completion of a Bachelor's degree in a STEM or related field.
  • Specific experience with molecular biology, biochemistry, tissue culture and/or laboratory animals is a plus.
  • Analytical skills to resolve problems that require the use of basic scientific, mathematical, or technical principles.
  • Ability to communicate effectively both orally and in writing.
  • Outstanding analytical and interpersonal skills are essential.

 
Please note: During a public health emergency, individuals in this role may be expected to take on additional duties to respond to organizational needs.

BCH offers competitive compensation and benefits.

Boston Children’s Hospital is an Equal Opportunity / Affirmative Action Employer. Qualified applicants will receive consideration for employment without regard to their race, color, religion, national origin, sex, sexual orientation, gender identity, protected veteran status or disability

More Information and Application

 


Research Assistant I - Kim Lab

56969BR

Medicine-Hematology/Oncology

Job Posting Description

The Stem Cell Program at Boston Children's Hospital seeks applications from highly motivated candidates for the position of Research Assistant I in the Carla Kim Laboratory, which is focused on the study of lung stem cell biology, regenerative medicine and lung cancer research. Candidate will have the opportunity to support multiple research projects and will conduct a variety of techniques such as DNA/RNA isolation, PCR, immunohistochemistry, molecular cloning, tissue culture and other molecular biology techniques. This is an excellent transition opportunity for a recent college graduate interested in pursuing further graduate or medical education after 2 years. Previous Kim lab assistants have been co-authors on several papers and are now enrolled in highly competitive medical and graduate school programs.
 
This Research Assistant I will be responsible for: 

  • Under immediate supervision, performs a variety of routine and specialized laboratory experimental, specimen preparations and experimental procedures for the purpose of research. Assists in the use of specialized laboratory equipment and analysis of data generated by this equipment
  • According to prescribed protocols and assigned schedules, performs a variety of routine laboratory experiments and procedures, utilizing standard laboratory equipment, recording and checking results for completeness and accuracy.
  • Assists in troubleshooting procedures if experimental results are unexpected or quality of specimens is poor.
  • Performs the following techniques typically required for the laboratory/study:
    • Maintains records of results and methodologies in a log of work performed.
    • Maintains equipment, lab area and supplies in a neat professional manner.
    • Sterilize and clean glassware, prepare media and other materials using appropriate procedures.
    • Inventories supplies alerts supervisor to needed supplies, or mixes standard reagents.
    • Processes order for supplies and/or animals. Attends courses in safety procedures for handling, storage and disposal of biohazardous, flammable, corrosive and toxic materials.
    • Carries out all laboratory activities in compliance with applicable regulations and protocols.
  • Conducts literature searches and reviews, compiling information for journals and suggesting uses for new techniques to the P.I.
  • Attends courses, lectures and conferences to further own knowledge of research and laboratory techniques, consulting with other researchers and technicians to exchange information.
  • Contributes to the team within and between departments and organizations.


To qualify, you must have:

  • The knowledge of theories, principles, and concepts acquired through completion of a Bachelor's degree in a STEM or related field.
  • Specific experience with molecular biology, biochemistry, tissue culture and/or laboratory animals is a plus.
  • Analytical skills to resolve problems that require the use of basic scientific, mathematical, or technical principles.
  • Ability to communicate effectively both orally and in writing.
  • Outstanding analytical and interpersonal skills are essential.

 
Please note: During a public health emergency, individuals in this role may be expected to take on additional duties to respond to organizational needs.

BCH offers competitive compensation and benefits.

Boston Children’s Hospital is an Equal Opportunity / Affirmative Action Employer. Qualified applicants will receive consideration for employment without regard to their race, color, religion, national origin, sex, sexual orientation, gender identity, protected veteran status or disability

More Information and Application.


Protein Sciences Specialist

The Harvard Medical School Therapeutics Translation is seeking an individual to join its scientific team, in support of our drug discovery effort against emerging pathogens.  The candidate would work collaboratively with several labs at HMS and the affiliated hospitals as a key contributor for ongoing structural biology efforts assisting corona virus related drug discovery programs. This will include solving novel structures of both viral and host proteins and routine co-structures of small and large molecules with their target proteins.  The successful candidate will engage in all aspects of structural biology including protein production, crystallization and structure determination.  The position will be part of an interdisciplinary team, working with design chemists, biochemists, virologists and pharmacologists across several ongoing projects. These team interactions will be both in person, and within the virtual environment. 

The preferred candidate would possess:

  • A PhD in protein science, structural biology or a related discipline
  • 2-3 years of additional experience in protein purification and structure determination by x-ray crystallography

Additional skills

  • Track record of independence in structural biology projects
  • Ability to work within a team environment, both in person and virtually
  • Good presentation and written communication skills
  • An interest in multidisciplinary research and therapeutics discovery

This is a 2-year term position.

Harvard is an Affirmative Action/Equal Opportunity Employer. Applications from women and minority candidates are strongly encouraged. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions or any other characteristic protected by law.

To apply, please submit a cover letter and CV to:
Dr. Mark Namchuk, mark_namchuk@hms.harvard.edu
Dr. Stephen Blacklow, Stephen_blacklow@hms.harvard.edu
Dr. Stephen Harrison, schadmin@crystal.harvard.edu

In the Subject line of your email, please write: Protein Sciences Specialist


Administrative Coordinator, Perrimon Lab, Boston, MA 

Howard Hughes Medical Institute (HHMI) is an independent, ever-evolving philanthropy that supports basic biomedical scientists and educators with the potential for transformative impact. We make long-term investments in people, not just projects, because we believe in the power of individuals to make breakthroughs over time. HHMI scientists have radically advanced the understanding of cells, the brain, the immune system, the development of organs, and how to treat many diseases.. Founded in 1953 by aviator and industrialist Howard R. Hughes, HHMI is headquartered in Chevy Chase, Maryland, and employs more than 2,500 people across the U.S. 

At HHMI, you are not just an employee – you are a part of a creative and talented team with colleagues whose expertise ranges from biomedical research to investment management, from information technology to law. We encourage collaborative and results-driven working styles and offer an adaptable environment where employees can function at their highest level. As HHMI scientists continue to push boundaries in laboratories and classrooms, you can be sure that your contributions while working at HHMI are making a difference. 

Dr. Norbert Perrimon’s lab in the Department of Genetics at Harvard Medical School is seeking an Administrative Coordinator to support their lab. This position provides high level administrative support to the Investigator and research staff in a fast-paced environment. The lab wants to understand how cells, tissues, and organs communicate during development. A more thorough understanding of these events can help elucidate how different tissues and cell types integrate within an organ, and how complex phenotypes arise in animals. More information can be found on their website: https://perrimon.med.harvard.edu/ 

Due to the fast-paced nature of the work of the lab, ideal candidates are people who thrive in quickly evolving environment and who have a strong ability to multitask, as well as have a strong understanding of management of large grants portfolios. This role is best fit for someone who is a self-starter and proactive in their support style – and someone who is passionate about the research work that the lab is conducting. 

PRINCIPLE RESPONSIBILITIES 

– Track grant and HHMI expenditures to facilitate efficient spending and provide monthly updates to the PI and lab, as well as ensure compliance with NIH regulations 

– Provide administrative support to the Investigator and ~50 lab members 

– Prepare all administrative materials for grant applications and progress reports such as biosketches, budget justifications, and other support documents 

– Assist HR with hiring and on-boarding personnel for positions within the lab 

– Arrange travel for Dr. Perrimon 

– Process reimbursements 

– Order lab supplies and arrange for equipment maintenance 

– Serve as key liaison with HMS departments and HHMI 

– Manage lab website 

– Assist with publication submissions 

– Prepare and monitor material transfer agreements 

– Process shipping labels and associated import / export information 

– Prepare slides and presentations for meetings and publications 

– Draft letters and correspondence 

REQUIRED SKILLS 

– Prior experiencing in grants management / budget oversight for a large portfolio from a variety of sources (NIH, DoD, foundations) 

– Ability to assess rolling tasks in busy lab and prioritize accordingly 

– Excellent organization skills 

– 4-7 years of prior Administrative experience in a laboratory setting 

– Ability to work collaboratively with diverse group of lab personnel, as well as department personnel 

– Strong computer skills, preferably on the Mac platform, including demonstrated proficiency with Microsoft Office applications and graphics programs such as PowerPoint and Photoshop. 

– Ability to work independently, use good judgment, meet tight deadlines and show initiative 

Preferred Qualifications: 

– Familiarity with Harvard systems such as HCOM and GMAS 

– Administrative experience in an academic laboratory 

– Bachelor’s degree 

HHMI is an Equal Opportunity Employer. 

Interested? Apply here