Genetics Research Reports

(Research originally featured on front page of site)

March 30, 2017

Spt5 Plays Vital Roles in the Control of Sense and Antisense Transcription Elongation. Ameet Shetty, Scott P. Kallgren, Carina Demel, Kerstin C. Maier, Dan Spatt, Burak H. Alver, Patrick Cramer, Peter J. Park, Fred Winston (Molecular Cell)

March 30, 2017

Simultaneous mapping of active DNA demethylation and sister chromatid exchange in single cells. Xiaoji Wu, Azusa Inoue, Tsukasa Suzuki, and Yi Zhang. (Genes and Development) 

Feb 15, 2017

A molecular census of arcuate hypothalamus and median eminence cell types​.  (Nature Neuroscience)

Feb 13, 2017

G1 cyclins link proliferation, pluripotency and Differentiation of embryonic stem cells. (Nature Cell Biology)

Dec 2016

Destabilization of B2 RNA by EZH2 Activates the Stress (Cell)

Dec 16, 2016

Reprogramming protein kinase substrate specificity through synthetic mutation​s  (BiorXiv)

August 2016

Cysteine Sulfenylation Directs IRE-1 to Activate the SKN-1/Nrf2 Antioxidant Response. (Mol Cell)

Feb 25, 2016

Schizophrenia risk from complex variation of complement component 4 (Nature)

Dec 14, 2015 

De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies (Science)

Jun 08, 2015    

Comprehensive serological profiling of human populations using a synthetic human virome (Science)

May 01, 2015 

Native Elongating Transcript Sequencing Reveals Human Transcriptional Activity at Nucleotide Resolution (Cell)

May 01, 2015

 Bending Gradients: How the Intestinal Stem Cell Gets Its Home (Cell)

Apr 30, 2015   

Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders (Cell)

 Jan 29, 2014  

Lung Stem Cell Differentiation in Mice Directed by Endothelial Cells via a BMP4-NFATc1-Thrombospondin-1 Axis (Cell)

Dec 10, 2013 

Nonenzymatic Template-Directed RNA Synthesis Inside Model Protocells (Science)

Oct 21, 2013 

Genomically Recoded Organisms Expand Biological Functions (Science)

Oct 18, 2013

Probing the Limits of Genetics Recoding in Essential Genes

Jun 28, 2013 

 Ikbkap/Elp1 Deficiency Causes Male Infertility by Disrupting Meiotic Progression (PLoS Genetics)

Mar 07, 2013

Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators (Science)

Dec 28, 2012  

Versatile design and synthesis platform for visualizing genomes with Oligopaint FISH probes (PNAS)

Oct 30, 2012   

The Requirement for Cyclin D Function in Tumor Maintenance (Cancer Cell)

Aug 28, 2012

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins (Nature)

Aug 28, 2012

Proto-gene model of de novo gene birth (Nature) 

Jul 13, 2012 

Reconstructing Native American population history

Feb 22, 2012 

 A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

Oct 04, 2011   

Denisova Admixture and the First Modern Human Dispersals into Southeast Asia and Oceania

Aug 23, 2011  

Drug Extends the Lives of Obese Mice by Inducing Lean Physiology

Aug 04, 2011 

Impaired Respiratory and Body Temperature Control Upon Acute Serotonergic Neuron Inhibition

Jul 27, 2011

The landscape of recombination in African Americans

Jun 12, 2010 

Primary tumor genotype is an important determinant of identification of lung cancer propagating cells.

May 07, 2010    

A Draft Sequence of the Neandertal Genome

Sep 28, 2009

A new system for functional analysis of neural networks

Sep 28, 2009 

A twin spot generator allows lineage analysis of adjacent embryonic cells

Sep 18, 2009 

Clues to a riddle in dosage compensation

Sep 18, 2009 

A method for genome-wide generation of diversity

Jul 09, 2009 

Genes of reproduction and cellular immortality

Jul 09, 2009

Random acts of concentration

Jul 09, 2009 

Molecular analysis of a classic experiment

Jul 09, 2009 

Enriching for genomic targets of interest

Jun 08, 2009

Weaknesses of Cancer Cells Containing RAS Mutations Discovered