Brian Seed headshot

Brian Seed, Ph.D.

Professor of Genetics, Harvard Medical School
Principal Investigator, Center for Computational and Integrative Biology, Massachusetts General Hospital
617-726-5975
Seed Lab Website
CARMA1 is critical for the development of allergic airway inflammation in a murine model of asthma.
Authors: Authors: Medoff BD, Seed B, Jackobek R, Zora J, Yang Y, Luster AD, Xavier R.
J Immunol
View full abstract on Pubmed
Expression cloning screen for modifiers of amyloid precursor protein shedding.
Authors: Authors: Schöbel S, Neumann S, Seed B, Lichtenthaler SF.
Int J Dev Neurosci
View full abstract on Pubmed
B cell maturation antigen, the receptor for a proliferation-inducing ligand and B cell-activating factor of the TNF family, induces antigen presentation in B cells.
Authors: Authors: Yang M, Hase H, Legarda-Addison D, Varughese L, Seed B, Ting AT.
J Immunol
View full abstract on Pubmed
Identification of eosinophil lineage-committed progenitors in the murine bone marrow.
Authors: Authors: Iwasaki H, Mizuno S, Mayfield R, Shigematsu H, Arinobu Y, Seed B, Gurish MF, Takatsu K, Akashi K.
J Exp Med
View full abstract on Pubmed
PDZ domains and the politics of polarity in lymphocytes.
Authors: Authors: Xavier R, Seed B.
Immunity
View full abstract on Pubmed
Large-scale screens for cDNAs with in vivo activity.
Authors: Authors: Ting A, Lichtenthaler S, Xavier R, Na SY, Rabizadeh S, Holmes T, Seed B.
Novartis Found Symp
View full abstract on Pubmed
Differential transplantability of tumor-associated stromal cells.
Authors: Authors: Duda DG, Fukumura D, Munn LL, Booth MF, Brown EB, Huang P, Seed B, Jain RK.
Cancer Res
View full abstract on Pubmed
The knockout mouse project.
Authors: Authors: Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, Koller BH, Lloyd KC, Magnuson T, Moore MW, Nagy A, Pollock JD, Roses AD, Sands AT, Seed B, Skarnes WC, Snoddy J, Soriano P, Stewart DJ, Stewart F, Stillman B, Varmus H, Varticovski L, Verma IM, Vogt TF, von Melchner H, Witkowski J, Woychik RP, Wurst W, Yancopoulos GD, Young SG, Zambrowicz B.
Nat Genet
View full abstract on Pubmed
Discs large (Dlg1) complexes in lymphocyte activation.
Authors: Authors: Xavier R, Rabizadeh S, Ishiguro K, Andre N, Ortiz JB, Wachtel H, Morris DG, Lopez-Ilasaca M, Shaw AC, Swat W, Seed B.
J Cell Biol
View full abstract on Pubmed
The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death.
Authors: Authors: Rabizadeh S, Xavier RJ, Ishiguro K, Bernabeortiz J, Lopez-Ilasaca M, Khokhlatchev A, Mollahan P, Pfeifer GP, Avruch J, Seed B.
J Biol Chem
View full abstract on Pubmed