Brian Seed, Ph.D.
Professor of Genetics, Harvard Medical School
Principal Investigator, Center for Computational and Integrative Biology, Massachusetts General Hospital
Integrins and inside-out signal transduction: converging signals from PKC and PIP3.
RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis.
Alpha L beta 2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule.
Authors: Authors: Kolanus W, Nagel W, Schiller B, Zeitlmann L, Godar S, Stockinger H, Seed B.
Cell
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Cell
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Codon usage limitation in the expression of HIV-1 envelope glycoprotein.
Clustered syk tyrosine kinase domains trigger phagocytosis.
Authors: Authors: Greenberg S, Chang P, Wang DC, Xavier R, Seed B.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination.
Authors: Authors: Li Z, Otevrel T, Gao Y, Cheng HL, Seed B, Stamato TD, Taccioli GE, Alt FW.
Cell
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Cell
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PSGL-1 recognition of P-selectin is controlled by a tyrosine sulfation consensus at the PSGL-1 amino terminus.
Developments in expression cloning.
RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death.
Initiation of signal transduction by receptor aggregation: role of nonreceptor tyrosine kinases.