Christine Seidman headshot

Christine Edry Seidman, M.D.

Director, Cardiovascular Genetics Center
Thomas W. Smith Professor of Medicine, Harvard Medical School
617-432-7838
Seidman Lab Website
The Congenital Heart Disease Genetic Network Study: rationale, design, and early results.
Authors: Authors: Gelb B, Brueckner M, Chung W, Goldmuntz E, Kaltman J, Kaski JP, Kim R, Kline J, Mercer-Rosa L, Porter G, Roberts A, Rosenberg E, Seiden H, Seidman C, Sleeper L, Tennstedt S, Kaltman J, Schramm C, Burns K, Pearson G, Rosenberg E.
Circ Res
View full abstract on Pubmed
Exercise training improves cardiac function and attenuates arrhythmia in CPVT mice.
Authors: Authors: Kurtzwald-Josefson E, Hochhauser E, Katz G, Porat E, Seidman JG, Seidman CE, Chepurko Y, Shainberg A, Eldar M, Arad M.
J Appl Physiol (1985)
View full abstract on Pubmed
Hypertrophic cardiomyopathy: translating cellular cross talk into therapeutics.
Authors: Authors: Teekakirikul P, Padera RF, Seidman JG, Seidman CE.
J Cell Biol
View full abstract on Pubmed
Subtle abnormalities in contractile function are an early manifestation of sarcomere mutations in dilated cardiomyopathy.
Authors: Authors: Lakdawala NK, Thune JJ, Colan SD, Cirino AL, Farrohi F, Rivero J, McDonough B, Sparks E, Orav EJ, Seidman JG, Seidman CE, Ho CY.
Circ Cardiovasc Genet
View full abstract on Pubmed
Burden of rare sarcomere gene variants in the Framingham and Jackson Heart Study cohorts.
Authors: Authors: Bick AG, Flannick J, Ito K, Cheng S, Vasan RS, Parfenov MG, Herman DS, DePalma SR, Gupta N, Gabriel SB, Funke BH, Rehm HL, Benjamin EJ, Aragam J, Taylor HA, Fox ER, Newton-Cheh C, Kathiresan S, O'Donnell CJ, Wilson JG, Altshuler DM, Hirschhorn JN, Seidman JG, Seidman C.
Am J Hum Genet
View full abstract on Pubmed
Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development.
Authors: Authors: Lage K, Greenway SC, Rosenfeld JA, Wakimoto H, Gorham JM, Segrè AV, Roberts AE, Smoot LB, Pu WT, Pereira AC, Mesquita SM, Tommerup N, Brunak S, Ballif BC, Shaffer LG, Donahoe PK, Daly MJ, Seidman JG, Seidman CE, Larsen LA.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Spectrum of somatic mitochondrial mutations in five cancers.
Authors: Authors: Larman TC, DePalma SR, Hadjipanayis AG, Protopopov A, Zhang J, Gabriel SB, Chin L, Seidman CE, Kucherlapati R, Seidman JG.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
A public resource facilitating clinical use of genomes.
Authors: Authors: Ball MP, Thakuria JV, Zaranek AW, Clegg T, Rosenbaum AM, Wu X, Angrist M, Bhak J, Bobe J, Callow MJ, Cano C, Chou MF, Chung WK, Douglas SM, Estep PW, Gore A, Hulick P, Labarga A, Lee JH, Lunshof JE, Kim BC, Kim JI, Li Z, Murray MF, Nilsen GB, Peters BA, Raman AM, Rienhoff HY, Robasky K, Wheeler MT, Vandewege W, Vorhaus DB, Yang JL, Yang L, Aach J, Ashley EA, Drmanac R, Kim SJ, Li JB, Peshkin L, Seidman CE, Seo JS, Zhang K, Rehm HL, Church GM.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
The Good SHP2 Association: a porthole into the genetics of congenital heart disease.
Authors: Authors: Gelb BD, Seidman CE.
Circ Cardiovasc Genet
View full abstract on Pubmed
Genetic testing for dilated cardiomyopathy in clinical practice.
Authors: Authors: Lakdawala NK, Funke BH, Baxter S, Cirino AL, Roberts AE, Judge DP, Johnson N, Mendelsohn NJ, Morel C, Care M, Chung WK, Jones C, Psychogios A, Duffy E, Rehm HL, White E, Seidman JG, Seidman CE, Ho CY.
J Card Fail
View full abstract on Pubmed