Christine Edry Seidman

Christine Edry Seidman, M.D.

Director, Cardiovascular Genetics Center

Thomas W. Smith Professor of Medicine, Harvard Medical School

617-432-7838

Publications

Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathy.

Authors: Authors: Jiang J, Wakimoto H, Seidman JG, Seidman CE.
Science 2013-10-04
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An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: applications in mice with bone property altering Lrp5 mutations.

Authors: Authors: Ayturk UM, Jacobsen CM, Christodoulou DC, Gorham J, Seidman JG, Seidman CE, Robling AG, Warman ML.
J Bone Miner Res 2013-10-01
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HOXA2 haploinsufficiency in dominant bilateral microtia and hearing loss.

Authors: Authors: Brown KK, Viana LM, Helwig CC, Artunduaga MA, Quintanilla-Dieck L, Jarrin P, Osorno G, McDonough B, DePalma SR, Eavey RD, Seidman JG, Seidman CE.
Hum Mutat 2013-10-01
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Conundrum of sudden cardiac death: making sense of missense.

Authors: Authors: Ip JE, Seidman CE, Liu CF, Cheung JW, Thomas G, Markowitz SM, Lerman BB.
Circ Arrhythm Electrophysiol 2013-08-01
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A conversation with Christine Seidman. Interview by Ushma S. Neill.

Authors: Authors: Seidman C.
J Clin Invest 2013-07-01
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De novo mutations in histone-modifying genes in congenital heart disease.

Authors: Authors: Zaidi S, Choi M, Wakimoto H, Ma L, Jiang J, Overton JD, Romano-Adesman A, Bjornson RD, Breitbart RE, Brown KK, Carriero NJ, Cheung YH, Deanfield J, DePalma S, Fakhro KA, Glessner J, Hakonarson H, Italia MJ, Kaltman JR, Kaski J, Kim R, Kline JK, Lee T, Leipzig J, Lopez A, Mane SM, Mitchell LE, Newburger JW, Parfenov M, Pe'er I, Porter G, Roberts AE, Sachidanandam R, Sanders SJ, Seiden HS, State MW, Subramanian S, Tikhonova IR, Wang W, Warburton D, White PS, Williams IA, Zhao H, Seidman JG, Brueckner M, Chung WK, Gelb BD, Goldmuntz E, Seidman CE, Lifton RP.
Nature 2013-06-13
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Functional characterization of a novel mutation in NKX2-5 associated with congenital heart disease and adult-onset cardiomyopathy.

Authors: Authors: Costa MW, Guo G, Wolstein O, Vale M, Castro ML, Wang L, Otway R, Riek P, Cochrane N, Furtado M, Semsarian C, Weintraub RG, Yeoh T, Hayward C, Keogh A, Macdonald P, Feneley M, Graham RM, Seidman JG, Seidman CE, Rosenthal N, Fatkin D, Harvey RP.
Circ Cardiovasc Genet 2013-06-01
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Spatial transcriptional profile of the chick and mouse endocardial cushions identify novel regulators of endocardial EMT in vitro.

Authors: Authors: DeLaughter DM, Christodoulou DC, Robinson JY, Seidman CE, Baldwin HS, Seidman JG, Barnett JV.
J Mol Cell Cardiol 2013-06-01
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Elevated rates of force development and MgATP binding in F764L and S532P myosin mutations causing dilated cardiomyopathy.

Authors: Authors: Palmer BM, Schmitt JP, Seidman CE, Seidman JG, Wang Y, Bell SP, Lewinter MM, Maughan DW.
J Mol Cell Cardiol 2013-04-01
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Genetics of congenital heart disease: the glass half empty.

Authors: Authors: Fahed AC, Gelb BD, Seidman JG, Seidman CE.
Circ Res 2013-02-15
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