Christine Seidman headshot

Christine Edry Seidman, M.D.

Director, Cardiovascular Genetics Center
Thomas W. Smith Professor of Medicine, Harvard Medical School
617-432-7838
Seidman Lab Website
Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease.
Authors: Authors: Schlotter F, Halu A, Goto S, Blaser MC, Body SC, Lee LH, Higashi H, DeLaughter DM, Hutcheson JD, Vyas P, Pham T, Rogers MA, Sharma A, Seidman CE, Loscalzo J, Seidman JG, Aikawa M, Singh SA, Aikawa E.
Circulation
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Robust identification of deletions in exome and genome sequence data based on clustering of Mendelian errors.
Authors: Authors: Manheimer KB, Patel N, Richter F, Gorham J, Tai AC, Homsy J, Boskovski MT, Parfenov M, Goldmuntz E, Chung WK, Brueckner M, Tristani-Firouzi M, Srivastava D, Seidman JG, Seidman CE, Gelb BD, Sharp AJ.
Hum Mutat
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Dynamic Cellular Integration Drives Functional Assembly of the Heart's Pacemaker Complex.
Authors: Authors: Bressan M, Henley T, Louie JD, Liu G, Christodoulou D, Bai X, Taylor J, Seidman CE, Seidman JG, Mikawa T.
Cell Rep
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Genetic Pathogenesis of Hypertrophic and Dilated Cardiomyopathy.
Authors: Authors: Garfinkel AC, Seidman JG, Seidman CE.
Heart Fail Clin
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Human Induced Pluripotent Stem Cell Production and Expansion from Blood using a Non-Integrating Viral Reprogramming Vector.
Authors: Authors: Sharma A, Mücke M, Seidman CE.
Curr Protoc Mol Biol
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In vivo and In vitro methods to identify DNA sequence variants that alter RNA Splicing.
Authors: Authors: Patel PN, Gorham JM, Ito K, Seidman CE.
Curr Protoc Hum Genet
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Robust identification of mosaic variants in congenital heart disease.
Authors: Authors: Manheimer KB, Richter F, Edelmann LJ, D'Souza SL, Shi L, Shen Y, Homsy J, Boskovski MT, Tai AC, Gorham J, Yasso C, Goldmuntz E, Brueckner M, Lifton RP, Chung WK, Seidman CE, Seidman JG, Gelb BD.
Hum Genet
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Differentiation and Contractile Analysis of GFP-Sarcomere Reporter hiPSC-Cardiomyocytes.
Authors: Authors: Sharma A, Toepfer CN, Schmid M, Garfinkel AC, Seidman CE.
Curr Protoc Hum Genet
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CRISPR/Cas9-Mediated Fluorescent Tagging of Endogenous Proteins in Human Pluripotent Stem Cells.
Authors: Authors: Sharma A, Toepfer CN, Ward T, Wasson L, Agarwal R, Conner DA, Hu JH, Seidman CE.
Curr Protoc Hum Genet
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Force Generation via ß-Cardiac Myosin, Titin, and a-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions.
Authors: Authors: Chopra A, Kutys ML, Zhang K, Polacheck WJ, Sheng CC, Luu RJ, Eyckmans J, Hinson JT, Seidman JG, Seidman CE, Chen CS.
Dev Cell
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