Constance Cepko, Ph.D.
Bullard Professor of Genetics and Neuroscience, Harvard Medical School
Professor of Ophthalmology, Massachusetts Eye and Ear Infirmary
Investigator, Howard Hughes Medical Institute
Spatiotemporal patterns of neuronal subtype genesis suggest hierarchical development of retinal diversity.
Authors: Authors: West ER, Lapan SW, Lee C, Kajderowicz KM, Li X, Cepko CL.
Cell Rep
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Cell Rep
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Targeting Microglia to Treat Degenerative Eye Diseases.
Development and diversification of bipolar interneurons in the mammalian retina.
Augmentation of CD47-SIRPa signaling protects cones in genetic models of retinal degeneration.
AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa.
Authors: Authors: Xue Y, Wang SK, Rana P, West ER, Hong CM, Feng H, Wu DM, Cepko CL.
Elife
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Elife
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Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses.
Authors: Authors: Chan YK, Wang SK, Chu CJ, Copland DA, Letizia AJ, Costa Verdera H, Chiang JJ, Sethi M, Wang MK, Neidermyer WJ, Chan Y, Lim ET, Graveline AR, Sanchez M, Boyd RF, Vihtelic TS, Inciong RGCO, Slain JM, Alphonse PJ, Xue Y, Robinson-McCarthy LR, Tam JM, Jabbar MH, Sahu B, Adeniran JF, Muhuri M, Tai PWL, Xie J, Krause TB, Vernet A, Pezone M, Xiao R, Liu T, Wang W, Kaplan HJ, Gao G, Dick AD, Mingozzi F, McCall MA, Cepko CL, Church GM.
Sci Transl Med
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Sci Transl Med
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Clinical Assessment and Validation of a Rapid and Sensitive SARS-CoV-2 Test Using Reverse Transcription Loop-Mediated Isothermal Amplification Without the Need for RNA Extraction.
Authors: Authors: Anahtar MN, McGrath GEG, Rabe BA, Tanner NA, White BA, Lennerz JKM, Branda JA, Cepko CL, Rosenberg ES.
Open Forum Infect Dis
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Open Forum Infect Dis
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Nrf2 overexpression rescues the RPE in mouse models of retinitis pigmentosa.
Authors: Authors: Wu DM, Ji X, Ivanchenko MV, Chung M, Piper M, Rana P, Wang SK, Xue Y, West E, Zhao SR, Xu H, Cicconet M, Xiong W, Cepko CL.
JCI Insight
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JCI Insight
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In Situ Detection of Adeno-associated Viral Vector Genomes with SABER-FISH.
Authors: Authors: Wang SK, Lapan SW, Hong CM, Krause TB, Cepko CL.
Mol Ther Methods Clin Dev
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Mol Ther Methods Clin Dev
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SARS-CoV-2 detection using isothermal amplification and a rapid, inexpensive protocol for sample inactivation and purification.