Constance Cepko, Ph.D.
Bullard Professor of Genetics and Neuroscience, Harvard Medical School
Professor of Ophthalmology, Massachusetts Eye and Ear Infirmary
Investigator, Howard Hughes Medical Institute
Vertebrate neural cell-fate determination: lessons from the retina.
The p57Kip2 cyclin kinase inhibitor is expressed by a restricted set of amacrine cells in the rodent retina.
Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure.
Authors: Authors: Chang B, Smith RS, Peters M, Savinova OV, Hawes NL, Zabaleta A, Nusinowitz S, Martin JE, Davisson ML, Cepko CL, Hogan BL, John SW.
BMC Genet
View full abstract on Pubmed
BMC Genet
View full abstract on Pubmed
The external granule layer of the developing chick cerebellum generates granule cells and cells of the isthmus and rostral hindbrain.
Two homeobox genes define the domain of EphA3 expression in the developing chick retina.
Control of Müller glial cell proliferation and activation following retinal injury.
p57(Kip2) regulates progenitor cell proliferation and amacrine interneuron development in the mouse retina.
All Brn3 genes can promote retinal ganglion cell differentiation in the chick.
Authors: Authors: Liu W, Khare SL, Liang X, Peters MA, Liu X, Cepko CL, Xiang M.
Development
View full abstract on Pubmed
Development
View full abstract on Pubmed
Misexpression of basic helix-loop-helix genes in the murine cerebral cortex affects cell fate choices and neuronal survival.
rax, Hes1, and notch1 promote the formation of Müller glia by postnatal retinal progenitor cells.
Authors: Authors: Furukawa T, Mukherjee S, Bao ZZ, Morrow EM, Cepko CL.
Neuron
View full abstract on Pubmed
Neuron
View full abstract on Pubmed