Constance Cepko, Ph.D.
Bullard Professor of Genetics and Neuroscience, Harvard Medical School
Professor of Ophthalmology, Massachusetts Eye and Ear Infirmary
Investigator, Howard Hughes Medical Institute
A gene regulatory network controls the binary fate decision of rod and bipolar cells in the vertebrate retina.
Intrinsically different retinal progenitor cells produce specific types of progeny.
The Lgr5 transgene is expressed specifically in glycinergic amacrine cells in the mouse retina.
Authors: Authors: Sukhdeo K, Koch CE, Miller TE, Zhou H, Rivera M, Yan K, Cepko CL, Lathia JD, Rich JN.
Exp Eye Res
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Exp Eye Res
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Analysis of gene expression in wild-type and Notch1 mutant retinal cells by single cell profiling.
Authors: Authors: Mizeracka K, Trimarchi JM, Stadler MB, Cepko CL.
Dev Dyn
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Dev Dyn
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A nanobody-based system using fluorescent proteins as scaffolds for cell-specific gene manipulation.
Authors: Authors: Tang JC, Szikra T, Kozorovitskiy Y, Teixiera M, Sabatini BL, Roska B, Cepko CL.
Cell
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Cell
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Notch1 is required in newly postmitotic cells to inhibit the rod photoreceptor fate.
Otx2 and Onecut1 promote the fates of cone photoreceptors and horizontal cells and repress rod photoreceptors.
Authors: Authors: Emerson MM, Surzenko N, Goetz JJ, Trimarchi J, Cepko CL.
Dev Cell
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Dev Cell
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Pseudotyped retroviruses for infecting axolotl in vivo and in vitro.
Authors: Authors: Whited JL, Tsai SL, Beier KT, White JN, Piekarski N, Hanken J, Cepko CL, Tabin CJ.
Development
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Development
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Retinal gene therapy coming of age.
Transsynaptic tracing with vesicular stomatitis virus reveals novel retinal circuitry.
Authors: Authors: Beier KT, Borghuis BG, El-Danaf RN, Huberman AD, Demb JB, Cepko CL.
J Neurosci
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J Neurosci
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