The Ausubel laboratory uses genetic, genomic, and chemical genetic approaches to: (1) elucidate the molecular basis of microbial pathogenesis in the bacterial pathogens Pseudomonas aeruginosa and Pseudomonas syringae and (2) identify the components of the signaling pathways involved in the host innate immune response in the plant Arabidopsis thaliana and the nematode Caenorhabditis elegans.
Arabidopsis thaliana mutant that develops as a light-grown plant in the absence of light.
Authors: Authors: Chory J, Peto C, Feinbaum R, Pratt L, Ausubel F.
Cell
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Cell
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Different Roles for Phytochrome in Etiolated and Green Plants Deduced from Characterization of Arabidopsis thaliana Mutants.
Authors: Authors: Chory J, Peto CA, Ashbaugh M, Saganich R, Pratt L, Ausubel F.
Plant Cell
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Plant Cell
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General method for site-directed mutagenesis in Escherichia coli O18ac:K1:H7: deletion of the inducible superoxide dismutase gene, sodA, does not diminish bacteremia in neonatal rats.
The central domain of Rhizobium meliloti NifA is sufficient to activate transcription from the R. meliloti nifH promoter.
A dual-labeling method for identifying differentially expressed genes: use in the identification of cDNA clones that hybridize to RNAs whose abundance in tomato flowers is potentially regulated by gibberellins.
Identification of a gene linked to Rhizobium meliloti ntrA whose product is homologous to a family to ATP-binding proteins.
Authors: Authors: Albright LM, Ronson CW, Nixon BT, Ausubel FM.
J Bacteriol
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J Bacteriol
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Rhizobium meliloti 1021 has three differentially regulated loci involved in glutamine biosynthesis, none of which is essential for symbiotic nitrogen fixation.
Authors: Authors: de Bruijn FJ, Rossbach S, Schneider M, Ratet P, Messmer S, Szeto WW, Ausubel FM, Schell J.
J Bacteriol
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J Bacteriol
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Prokaryotic signal transduction mediated by sensor and regulator protein pairs.
Interference between Rhizobium meliloti and Rhizobium trifolii nodulation genes: genetic basis of R. meliloti dominance.
Authors: Authors: Debellé F, Maillet F, Vasse J, Rosenberg C, de Billy F, Truchet G, Dénarié J, Ausubel FM.
J Bacteriol
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J Bacteriol
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Specialized binary vector for plant transformation: expression of the Arabidopsis thaliana AHAS gene in Nicotiana tabacum.
Authors: Authors: Olszewski NE, Martin FB, Ausubel FM.
Nucleic Acids Res
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Nucleic Acids Res
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