Gary B. Ruvkun

Gary B. Ruvkun, Ph.D.

Professor of Genetics, Harvard Medical School

Department of Molecular Biology, Massachusetts General Hospital

617-726-5959

Ruvkun Lab Website

Publications

Caenorhabditis elegans SynMuv B gene activity is down-regulated during a viral infection to enhance RNA interference.

Authors: Authors: Seetharaman A, Galagali H, Linarte E, Liu MHX, Cohen JD, Chetal K, Sadreyev R, Tate AJ, Montgomery TA, Ruvkun G.
bioRxiv 2024-07-16
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Mutations in nucleotide metabolism genes bypass proteasome defects in png-1/NGLY1-deficient Caenorhabditis elegans.

Authors:
PLoS Biol 2024-07-11
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CMTR-1 RNA methyltransferase mutations activate widespread expression of a dopaminergic neuron-specific mitochondrial complex I gene.

Authors: Authors: Meisel JD, Wiesenthal PP, Mootha VK, Ruvkun G.
Curr Biol 2024-05-24
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Hypoxia-inducible factor induces cysteine dioxygenase and promotes cysteine homeostasis in Caenorhabditis elegans.

Authors: Authors: Warnhoff K, Bhattacharya S, Snoozy J, Breen PC, Ruvkun G.
Elife 2024-02-13
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Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism.

Authors: Authors: Meisel JD, Miranda M, Skinner OS, Wiesenthal PP, Wellner SM, Jourdain AA, Ruvkun G, Mootha VK.
Cell 2024-02-01
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Hypoxia-inducible factor induces cysteine dioxygenase and promotes cysteine homeostasis in Caenorhabditis elegans.

Authors: Authors: Warnhoff K, Bhattacharya S, Snoozy J, Breen PC, Ruvkun G.
bioRxiv 2023-11-01
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DEPCOD: a tool to detect and visualize co-evolution of protein domains.

Authors: Authors: Ji F, Bonilla G, Krykbaev R, Ruvkun G, Tabach Y, Sadreyev RI.
Nucleic Acids Res 2022-05-10
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Author Correction: Lipid signalling couples translational surveillance to systemic detoxification in Caenorhabditis elegans.

Authors: Authors: Govindan JA, Jayamani E, Zhang X, Breen P, Larkins-Ford J, Mylonakis E, Ruvkun G.
Nat Cell Biol 2022-04-11
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moc-6/MOCS2A is necessary for molybdenum cofactor synthesis in C. elegans.

Authors: Authors: Snoozy J, Breen PC, Ruvkun G, Warnhoff K.
MicroPubl Biol 2022-01-01
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Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility.

Authors: Authors: Charlesworth AG, Seroussi U, Lehrbach NJ, Renaud MS, Sundby AE, Molnar RI, Lao RX, Willis AR, Woock JR, Aber MJ, Diao AJ, Reinke AW, Ruvkun G, Claycomb JM.
Nucleic Acids Res 2021-07-30
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