Gary B. Ruvkun, Ph.D.
Professor of Genetics, Harvard Medical School
Department of Molecular Biology, Massachusetts General Hospital
Caenorhabditis elegans has scores of homoeobox-containing genes.
The Caenorhabditis elegans heterochronic gene lin-14 encodes a nuclear protein that forms a temporal developmental switch.
Molecular genetics of the Caenorhabditis elegans heterochronic gene lin-14.
Authors: Authors: Ruvkun G, Ambros V, Coulson A, Waterston R, Sulston J, Horvitz HR.
Genetics
View full abstract on Pubmed
Genetics
View full abstract on Pubmed
The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors.
The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products.
Authors: Authors: Herr W, Sturm RA, Clerc RG, Corcoran LM, Baltimore D, Sharp PA, Ingraham HA, Rosenfeld MG, Finney M, Ruvkun G, et al.
Genes Dev
View full abstract on Pubmed
Genes Dev
View full abstract on Pubmed
Specific protection of nucleotides in the lac operator from DMS methylation and DNase I nicking by crude bacterial cell extracts.
Directed transposon Tn5 mutagenesis and complementation analysis of Rhizobium meliloti symbiotic nitrogen fixation genes.
ISRm1: A Rhizobium meliloti insertion sequence that transposes preferentially into nitrogen fixation genes.
Authors: Authors: Ruvkun GB, Long SR, Meade HM, van den Bos RC, Ausubel FM.
J Mol Appl Genet
View full abstract on Pubmed
J Mol Appl Genet
View full abstract on Pubmed
Physical and genetic characterization of symbiotic and auxotrophic mutants of Rhizobium meliloti induced by transposon Tn5 mutagenesis.
Authors: Authors: Meade HM, Long SR, Ruvkun GB, Brown SE, Ausubel FM.
J Bacteriol
View full abstract on Pubmed
J Bacteriol
View full abstract on Pubmed
A general method for site-directed mutagenesis in prokaryotes.