Gary B. Ruvkun

Gary B. Ruvkun, Ph.D.

Professor of Genetics, Harvard Medical School

Department of Molecular Biology, Massachusetts General Hospital

617-726-5959

Ruvkun Lab Website

Publications

Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis.

Authors: Authors: Ast T, Meisel JD, Patra S, Wang H, Grange RMH, Kim SH, Calvo SE, Orefice LL, Nagashima F, Ichinose F, Zapol WM, Ruvkun G, Barondeau DP, Mootha VK.
Cell 2019-05-30
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Molybdenum cofactor transfer from bacteria to nematode mediates sulfite detoxification.

Authors: Authors: Warnhoff K, Ruvkun G.
Nat Chem Biol 2019-05-01
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Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression.

Authors: Authors: Lehrbach NJ, Breen PC, Ruvkun G.
Cell 2019-04-18
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Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity.

Authors: Authors: Lehrbach NJ, Ruvkun G.
Elife 2019-04-11
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Rhizobium induces DNA damage in Caenorhabditis elegans intestinal cells.

Authors: Authors: Kniazeva M, Ruvkun G.
Proc Natl Acad Sci U S A 2019-02-26
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Mitochondrial Dysfunction in C. elegans Activates Mitochondrial Relocalization and Nuclear Hormone Receptor-Dependent Detoxification Genes.

Authors: Authors: Mao K, Ji F, Breen P, Sewell A, Han M, Sadreyev R, Ruvkun G.
Cell Metab 2019-02-14
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Endoplasmic Reticulum Homeostasis Is Modulated by the Forkhead Transcription Factor FKH-9 During Infection of Caenorhabditis elegans.

Authors: Authors: Tillman EJ, Richardson CE, Cattie DJ, Reddy KC, Lehrbach NJ, Droste R, Ruvkun G, Kim DH.
Genetics 2018-12-01
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DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity.

Authors: Authors: Lin XX, Sen I, Janssens GE, Zhou X, Fonslow BR, Edgar D, Stroustrup N, Swoboda P, Yates JR, Ruvkun G, Riedel CG.
Nat Commun 2018-10-23
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Sequencing nothing: Exploring failure modes of nanopore sensing and implications for life detection.

Authors: Authors: Pontefract A, Hachey J, Zuber MT, Ruvkun G, Carr CE.
Life Sci Space Res (Amst) 2018-08-01
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Recent Molecular Genetic Explorations of Caenorhabditis elegans MicroRNAs.

Authors: Authors: Ambros V, Ruvkun G.
Genetics 2018-07-01
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