Gary B. Ruvkun

Gary B. Ruvkun, Ph.D.

Professor of Genetics, Harvard Medical School

Department of Molecular Biology, Massachusetts General Hospital

617-726-5959

Ruvkun Lab Website

Publications

The C. elegans DAF-2 insulin-like receptor is abundantly expressed in the nervous system and regulated by nutritional status.

Authors: Authors: Kimura KD, Riddle DL, Ruvkun G.
Cold Spring Harb Symp Quant Biol 2011-01-01
View full abstract on Pubmed

Cancer. Germ cell genes and cancer.

Authors: Authors: Wu X, Ruvkun G.
Science 2010-12-24
View full abstract on Pubmed

MLT-10 defines a family of DUF644 and proline-rich repeat proteins involved in the molting cycle of Caenorhabditis elegans.

Authors: Authors: Meli VS, Osuna B, Ruvkun G, Frand AR.
Mol Biol Cell 2010-05-15
View full abstract on Pubmed

RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.

Authors: Authors: Sebastiani P, Montano M, Puca A, Solovieff N, Kojima T, Wang MC, Melista E, Meltzer M, Fischer SE, Andersen S, Hartley SH, Sedgewick A, Arai Y, Bergman A, Barzilai N, Terry DF, Riva A, Anselmi CV, Malovini A, Kitamoto A, Sawabe M, Arai T, Gondo Y, Steinberg MH, Hirose N, Atzmon G, Ruvkun G, Baldwin CT, Perls TT.
PLoS One 2009-12-14
View full abstract on Pubmed

C. elegans major fats are stored in vesicles distinct from lysosome-related organelles.

Authors: Authors: O'Rourke EJ, Soukas AA, Carr CE, Ruvkun G.
Cell Metab 2009-11-01
View full abstract on Pubmed

A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants.

Authors: Authors: Curran SP, Wu X, Riedel CG, Ruvkun G.
Nature 2009-06-25
View full abstract on Pubmed

Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans.

Authors: Authors: Soukas AA, Kane EA, Carr CE, Melo JA, Ruvkun G.
Genes Dev 2009-02-15
View full abstract on Pubmed

Biosynthesis of the Caenorhabditis elegans dauer pheromone.

Authors: Authors: Butcher RA, Ragains JR, Li W, Ruvkun G, Clardy J, Mak HY.
Proc Natl Acad Sci U S A 2009-02-10
View full abstract on Pubmed

The most conserved genome segments for life detection on Earth and other planets.

Authors: Authors: Isenbarger TA, Carr CE, Johnson SS, Finney M, Church GM, Gilbert W, Zuber MT, Ruvkun G.
Orig Life Evol Biosph 2008-12-01
View full abstract on Pubmed

Fat metabolism links germline stem cells and longevity in C. elegans.

Authors: Authors: Wang MC, O'Rourke EJ, Ruvkun G.
Science 2008-11-07
View full abstract on Pubmed