George Church headshot

George Church, Ph.D.

617-432-7562
Church Lab Website
Multiplex base editing to convert TAG into TAA codons in the human genome.
Authors: Authors: Chen Y, Hysolli E, Chen A, Casper S, Liu S, Yang K, Liu C, Church G.
Nat Commun
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Recording gene expression order in DNA by CRISPR addition of retron barcodes.
Authors: Authors: Bhattarai-Kline S, Lear SK, Fishman CB, Lopez SC, Lockshin ER, Schubert MG, Nivala J, Church GM, Shipman SL.
Nature
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Why it is important to study human-monkey embryonic chimeras in a dish.
Authors: Authors: De Los Angeles A, Regenberg A, Mascetti V, Benvenisty N, Church G, Deng H, Izpisua Belmonte JC, Ji W, Koplin J, Loh YH, Niu Y, Pei D, Pera M, Pho N, Pinzon-Arteaga C, Saitou M, Silva JCR, Tao T, Trounson A, Warrier T, Zambidis ET.
Nat Methods
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Massively targeted evaluation of therapeutic CRISPR off-targets in cells.
Authors: Authors: Pan X, Qu K, Yuan H, Xiang X, Anthon C, Pashkova L, Liang X, Han P, Corsi GI, Xu F, Liu P, Zhong J, Zhou Y, Ma T, Jiang H, Liu J, Wang J, Jessen N, Bolund L, Yang H, Xu X, Church GM, Gorodkin J, Lin L, Luo Y.
Nat Commun
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Characterization of ColE1 Production for Robust tolC Plate Dual-Selection in E. coli.
Authors: Authors: Baas-Thomas MS, Oehm SB, Ostrov N, Church GM.
ACS Synth Biol
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Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder.
Authors: Authors: Lim ET, Chan Y, Dawes P, Guo X, Erdin S, Tai DJC, Liu S, Reichert JM, Burns MJ, Chan YK, Chiang JJ, Meyer K, Zhang X, Walsh CA, Yankner BA, Raychaudhuri S, Hirschhorn JN, Gusella JF, Talkowski ME, Church GM.
Nat Commun
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New intranasal and injectable gene therapy for healthy life extension.
Authors: Authors: Jaijyan DK, Selariu A, Cruz-Cosme R, Tong M, Yang S, Stefa A, Kekich D, Sadoshima J, Herbig U, Tang Q, Church G, Parrish EL, Zhu H.
Proc Natl Acad Sci U S A
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Towards practical and robust DNA-based data archiving using the yin-yang codec system.
Authors: Authors: Ping Z, Chen S, Zhou G, Huang X, Zhu SJ, Zhang H, Lee HH, Lan Z, Cui J, Chen T, Zhang W, Yang H, Xu X, Church GM, Shen Y.
Nat Comput Sci
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Orthogonally induced differentiation of stem cells for the programmatic patterning of vascularized organoids and bioprinted tissues.
Authors: Authors: Skylar-Scott MA, Huang JY, Lu A, Ng AHM, Duenki T, Liu S, Nam LL, Damaraju S, Church GM, Lewis JA.
Nat Biomed Eng
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Targeted intracellular delivery of Cas13 and Cas9 nucleases using bacterial toxin-based platforms.
Authors: Authors: Tian S, Liu Y, Appleton E, Wang H, Church GM, Dong M.
Cell Rep
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