George Church

George Church, Ph.D.

617-432-7562

Church Lab Website

Publications

Delivery of biomacromolecules for therapeutic genome editing.

Authors: Authors: Ping Y, Church GM.
Adv Drug Deliv Rev 2021-01-01
View full abstract on Pubmed

Neuronal Cell-type Engineering by Transcriptional Activation.

Authors: Authors: Liu S, Striebel J, Pasquini G, Ng AHM, Khoshakhlagh P, Church GM, Busskamp V.
Front Genome Ed 2021-01-01
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Transparency is key to ethical vaccine research.

Authors: Authors: Estep PW, Church GM.
Science 2020-12-18
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A machine learning toolkit for genetic engineering attribution to facilitate biosecurity.

Authors: Authors: Alley EC, Turpin M, Liu AB, Kulp-McDowall T, Swett J, Edison R, Von Stetina SE, Church GM, Esvelt KM.
Nat Commun 2020-12-08
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The biosecurity benefits of genetic engineering attribution.

Authors: Authors: Lewis G, Jordan JL, Relman DA, Koblentz GD, Leung J, Dafoe A, Nelson C, Epstein GL, Katz R, Montague M, Alley EC, Filone CM, Luby S, Church GM, Millett P, Esvelt KM, Cameron EE, Inglesby TV.
Nat Commun 2020-12-08
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Reprogramming to recover youthful epigenetic information and restore vision.

Authors: Authors: Lu Y, Brommer B, Tian X, Krishnan A, Meer M, Wang C, Vera DL, Zeng Q, Yu D, Bonkowski MS, Yang JH, Zhou S, Hoffmann EM, Karg MM, Schultz MB, Kane AE, Davidsohn N, Korobkina E, Chwalek K, Rajman LA, Church GM, Hochedlinger K, Gladyshev VN, Horvath S, Levine ME, Gregory-Ksander MS, Ksander BR, He Z, Sinclair DA.
Nature 2020-12-01
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Targeted intracellular degradation of SARS-CoV-2 via computationally optimized peptide fusions.

Authors: Authors: Chatterjee P, Ponnapati M, Kramme C, Plesa AM, Church GM, Jacobson JM.
Commun Biol 2020-11-23
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Pluripotent stem cell-derived CAR-macrophage cells with antigen-dependent anti-cancer cell functions.

Authors: Authors: Zhang L, Tian L, Dai X, Yu H, Wang J, Lei A, Zhu M, Xu J, Zhao W, Zhu Y, Sun Z, Zhang H, Hu Y, Wang Y, Xu Y, Church GM, Huang H, Weng Q, Zhang J.
J Hematol Oncol 2020-11-11
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A robust benchmark for detection of germline large deletions and insertions.

Authors: Authors: Zook JM, Hansen NF, Olson ND, Chapman L, Mullikin JC, Xiao C, Sherry S, Koren S, Phillippy AM, Boutros PC, Sahraeian SME, Huang V, Rouette A, Alexander N, Mason CE, Hajirasouliha I, Ricketts C, Lee J, Tearle R, Fiddes IT, Barrio AM, Wala J, Carroll A, Ghaffari N, Rodriguez OL, Bashir A, Jackman S, Farrell JJ, Wenger AM, Alkan C, Soylev A, Schatz MC, Garg S, Church G, Marschall T, Chen K, Fan X, English AC, Rosenfeld JA, Zhou W, Mills RE, Sage JM, Davis JR, Kaiser MD, Oliver JS, Catalano AP, Chaisson MJP, Spies N, Sedlazeck FJ, Salit M.
Nat Biotechnol 2020-11-01
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Author Correction: A robust benchmark for detection of germline large deletions and insertions.