George Church

George Church, Ph.D.

617-432-7562

Church Lab Website

Publications

Mutants of Cre recombinase with improved accuracy.

Authors: Authors: Eroshenko N, Church GM.
Nat Commun 2013-01-01
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On the design of clone-based haplotyping.

Authors: Authors: Lo C, Liu R, Lee J, Robasky K, Byrne S, Lucchesi C, Aach J, Church G, Bafna V, Zhang K.
Genome Biol 2013-01-01
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The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies.

Authors: Authors: Sok D, Laserson U, Laserson J, Liu Y, Vigneault F, Julien JP, Briney B, Ramos A, Saye KF, Le K, Mahan A, Wang S, Kardar M, Yaari G, Walker LM, Simen BB, St John EP, Chan-Hui PY, Swiderek K, Kleinstein SH, Kleinstein SH, Alter G, Seaman MS, Chakraborty AK, Koller D, Wilson IA, Church GM, Burton DR, Poignard P.
PLoS Pathog 2013-01-01
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Redirector: designing cell factories by reconstructing the metabolic objective.

Authors: Authors: Rockwell G, Guido NJ, Church GM.
PLoS Comput Biol 2013-01-01
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Molecular threading: mechanical extraction, stretching and placement of DNA molecules from a liquid-air interface.

Authors: Authors: Payne AC, Andregg M, Kemmish K, Hamalainen M, Bowell C, Bleloch A, Klejwa N, Lehrach W, Schatz K, Stark H, Marblestone A, Church G, Own CS, Andregg W.
PLoS One 2013-01-01
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An analysis and validation pipeline for large-scale RNAi-based screens.

Authors: Authors: Plank M, Hu G, Silva AS, Wood SH, Hesketh EE, Janssens G, Macedo A, de Magalhães JP, Church GM.
Sci Rep 2013-01-01
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Manipulating replisome dynamics to enhance lambda Red-mediated multiplex genome engineering.

Authors: Authors: Lajoie MJ, Gregg CJ, Mosberg JA, Washington GC, Church GM.
Nucleic Acids Res 2012-12-01
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Essential genes as antimicrobial targets and cornerstones of synthetic biology.

Authors: Authors: Juhas M, Eberl L, Church GM.
Trends Biotechnol 2012-11-01
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Genome interpretation and assembly-recent progress and next steps.

Authors: Authors: Baker S, Joecker A, Church G, Snyder M, West J, Salzberg S, Worthey E, Smith T, Wang J, Reid JG.
Nat Biotechnol 2012-11-01
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Submicrometre geometrically encoded fluorescent barcodes self-assembled from DNA.

Authors: Authors: Lin C, Jungmann R, Leifer AM, Li C, Levner D, Church GM, Shih WM, Yin P.
Nat Chem 2012-10-01
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