Rapid in vitro production of single-stranded DNA.
Authors: Authors: Minev D, Guerra R, Kishi JY, Smith C, Krieg E, Said K, Hornick A, Sasaki HM, Filsinger G, Beliveau BJ, Yin P, Church GM, Shih WM.
Nucleic Acids Res
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Nucleic Acids Res
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Single-Cell CRISPR-Based Lineage Tracing in Mice.
Unified rational protein engineering with sequence-based deep representation learning.
Authors: Authors: Alley EC, Khimulya G, Biswas S, AlQuraishi M, Church GM.
Nat Methods
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Nat Methods
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Comprehensive AAV capsid fitness landscape reveals a viral gene and enables machine-guided design.
A single combination gene therapy treats multiple age-related diseases.
Authors: Authors: Davidsohn N, Pezone M, Vernet A, Graveline A, Oliver D, Slomovic S, Punthambaker S, Sun X, Liao R, Bonventre JV, Church GM.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Regulation of lifespan by neural excitation and REST.
Authors: Authors: Zullo JM, Drake D, Aron L, O'Hern P, Dhamne SC, Davidsohn N, Mao CA, Klein WH, Rotenberg A, Bennett DA, Church GM, Colaiácovo MP, Yankner BA.
Nature
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Nature
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Immuno-SABER enables highly multiplexed and amplified protein imaging in tissues.
Authors: Authors: Saka SK, Wang Y, Kishi JY, Zhu A, Zeng Y, Xie W, Kirli K, Yapp C, Cicconet M, Beliveau BJ, Lapan SW, Yin S, Lin M, Boyden ES, Kaeser PS, Pihan G, Church GM, Yin P.
Nat Biotechnol
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Nat Biotechnol
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Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism.
Authors: Authors: Scheiman J, Luber JM, Chavkin TA, MacDonald T, Tung A, Pham LD, Wibowo MC, Wurth RC, Punthambaker S, Tierney BT, Yang Z, Hattab MW, Avila-Pacheco J, Clish CB, Lessard S, Church GM, Kostic AD.
Nat Med
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Nat Med
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Functional genomics of the rapidly replicating bacterium Vibrio natriegens by CRISPRi.
Authors: Authors: Lee HH, Ostrov N, Wong BG, Gold MA, Khalil AS, Church GM.
Nat Microbiol
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Nat Microbiol
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The Advent of Human Life Data Economics.