George Church headshot

George Church, Ph.D.

617-432-7562
Church Lab Website
REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease.
Authors: Authors: Meyer K, Feldman HM, Lu T, Drake D, Lim ET, Ling KH, Bishop NA, Pan Y, Seo J, Lin YT, Su SC, Church GM, Tsai LH, Yankner BA.
Cell Rep
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CRISPR-C: circularization of genes and chromosome by CRISPR in human cells.
Authors: Authors: Møller HD, Lin L, Xiang X, Petersen TS, Huang J, Yang L, Kjeldsen E, Jensen UB, Zhang X, Liu X, Xu X, Wang J, Yang H, Church GM, Bolund L, Regenberg B, Luo Y.
Nucleic Acids Res
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Opinion: Advocating for science progress as a human right.
Authors: Authors: Porsdam Mann S, Donders Y, Mitchell C, Bradley VJ, Chou MF, Mann M, Church G, Porsdam H.
Proc Natl Acad Sci U S A
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Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow.
Authors: Authors: Brunk E, Chang RL, Xia J, Hefzi H, Yurkovich JT, Kim D, Buckmiller E, Wang HH, Cho BK, Yang C, Palsson BO, Church GM, Lewis NE.
Proc Natl Acad Sci U S A
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Establishing a Cell-Free Vibrio natriegens Expression System.
Authors: Authors: Wiegand DJ, Lee HH, Ostrov N, Church GM.
ACS Synth Biol
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CRISPR Guide RNA Cloning for Mammalian Systems.
Authors: Authors: Nageshwaran S, Chavez A, Cher Yeo N, Guo X, Lance-Byrne A, Tung A, Collins JJ, Church GM.
J Vis Exp
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Developmental barcoding of whole mouse via homing CRISPR.
Authors: Authors: Kalhor R, Kalhor K, Mejia L, Leeper K, Graveline A, Mali P, Church GM.
Science
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Biosensor libraries harness large classes of binding domains for construction of allosteric transcriptional regulators.
Authors: Authors: Juárez JF, Lecube-Azpeitia B, Brown SL, Johnston CD, Church GM.
Nat Commun
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Inter-homologue repair in fertilized human eggs?
Authors: Authors: Egli D, Zuccaro MV, Kosicki M, Church GM, Bradley A, Jasin M.
Nature
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An enhanced CRISPR repressor for targeted mammalian gene regulation.
Authors: Authors: Yeo NC, Chavez A, Lance-Byrne A, Chan Y, Menn D, Milanova D, Kuo CC, Guo X, Sharma S, Tung A, Cecchi RJ, Tuttle M, Pradhan S, Lim ET, Davidsohn N, Ebrahimkhani MR, Collins JJ, Lewis NE, Kiani S, Church GM.
Nat Methods
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