George Church

George Church, Ph.D.

617-432-7562

Church Lab Website

Publications

Engineering and optimising deaminase fusions for genome editing.

Authors: Authors: Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G.
Nat Commun 2016-11-02
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Design and characterization of a nanopore-coupled polymerase for single-molecule DNA sequencing by synthesis on an electrode array.

Authors: Authors: Stranges PB, Palla M, Kalachikov S, Nivala J, Dorwart M, Trans A, Kumar S, Porel M, Chien M, Tao C, Morozova I, Li Z, Shi S, Aberra A, Arnold C, Yang A, Aguirre A, Harada ET, Korenblum D, Pollard J, Bhat A, Gremyachinskiy D, Bibillo A, Chen R, Davis R, Russo JJ, Fuller CW, Roever S, Ju J, Church GM.
Proc Natl Acad Sci U S A 2016-11-01
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The whole genome sequences and experimentally phased haplotypes of over 100 personal genomes.

Authors: Authors: Mao Q, Ciotlos S, Zhang RY, Ball MP, Chin R, Carnevali P, Barua N, Nguyen S, Agarwal MR, Clegg T, Connelly A, Vandewege W, Zaranek AW, Estep PW, Church GM, Drmanac R, Peters BA.
Gigascience 2016-10-11
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A multifunctional AAV-CRISPR-Cas9 and its host response.

Authors: Authors: Chew WL, Tabebordbar M, Cheng JK, Mali P, Wu EY, Ng AH, Zhu K, Wagers AJ, Church GM.
Nat Methods 2016-10-01
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CRISPR-Cas9 System: Opportunities and Concerns.

Authors: Authors: Vasiliou SK, Diamandis EP, Church GM, Greely HT, Baylis F, Thompson C, Schmitt-Ulms G.
Clin Chem 2016-10-01
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Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli.

Authors: Authors: Napolitano MG, Landon M, Gregg CJ, Lajoie MJ, Govindarajan L, Mosberg JA, Kuznetsov G, Goodman DB, Vargas-Rodriguez O, Isaacs FJ, Söll D, Church GM.
Proc Natl Acad Sci U S A 2016-09-20
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Next stop for the CRISPR revolution: RNA-guided epigenetic regulators.

Authors: Authors: Vora S, Tuttle M, Cheng J, Church G.
FEBS J 2016-09-01
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Design, synthesis, and testing toward a 57-codon genome.

Authors: Authors: Ostrov N, Landon M, Guell M, Kuznetsov G, Teramoto J, Cervantes N, Zhou M, Singh K, Napolitano MG, Moosburner M, Shrock E, Pruitt BW, Conway N, Goodman DB, Gardner CL, Tyree G, Gonzales A, Wanner BL, Norville JE, Lajoie MJ, Church GM.
Science 2016-08-19
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Nanoscale imaging of RNA with expansion microscopy.

Authors: Authors: Chen F, Wassie AT, Cote AJ, Sinha A, Alon S, Asano S, Daugharthy ER, Chang JB, Marblestone A, Church GM, Raj A, Boyden ES.
Nat Methods 2016-08-01
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Molecular recordings by directed CRISPR spacer acquisition.

Authors: Authors: Shipman SL, Nivala J, Macklis JD, Church GM.
Science 2016-07-29
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