George Church headshot

George Church, Ph.D.

617-432-7562
Church Lab Website
BIOSAFETY. Safeguarding gene drive experiments in the laboratory.
Authors: Authors: Akbari OS, Bellen HJ, Bier E, Bullock SL, Burt A, Church GM, Cook KR, Duchek P, Edwards OR, Esvelt KM, Gantz VM, Golic KG, Gratz SJ, Harrison MM, Hayes KR, James AA, Kaufman TC, Knoblich J, Malik HS, Matthews KA, O'Connor-Giles KM, Parks AL, Perrimon N, Port F, Russell S, Ueda R, Wildonger J.
Science
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Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes.
Authors: Authors: Bhatt S, Gupta MK, Khamaisi M, Martinez R, Gritsenko MA, Wagner BK, Guye P, Busskamp V, Shirakawa J, Wu G, Liew CW, Clauss TR, Valdez I, El Ouaamari A, Dirice E, Takatani T, Keenan HA, Smith RD, Church G, Weiss R, Wagers AJ, Qian WJ, King GL, Kulkarni RN.
Cell Metab
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Fungal lysis by a soil bacterium fermenting cellulose.
Authors: Authors: Tolonen AC, Cerisy T, El-Sayyed H, Boutard M, Salanoubat M, Church GM.
Environ Microbiol
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Biotechnology. A prudent path forward for genomic engineering and germline gene modification.
Authors: Authors: Baltimore D, Berg P, Botchan M, Carroll D, Charo RA, Church G, Corn JE, Daley GQ, Doudna JA, Fenner M, Greely HT, Jinek M, Martin GS, Penhoet E, Puck J, Sternberg SH, Weissman JS, Yamamoto KR.
Science
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Highly efficient Cas9-mediated transcriptional programming.
Authors: Authors: Chavez A, Scheiman J, Vora S, Pruitt BW, Tuttle M, P R Iyer E, Lin S, Kiani S, Guzman CD, Wiegand DJ, Ter-Ovanesyan D, Braff JL, Davidsohn N, Housden BE, Perrimon N, Weiss R, Aach J, Collins JJ, Church GM.
Nat Methods
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Precision Chemistry for Precision Medicine.
Authors: Authors: Church GM.
ACS Cent Sci
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Improving microbial fitness in the mammalian gut by in vivo temporal functional metagenomics.
Authors: Authors: Yaung SJ, Deng L, Li N, Braff JL, Church GM, Bry L, Wang HH, Gerber GK.
Mol Syst Biol
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Fluorescent in situ sequencing (FISSEQ) of RNA for gene expression profiling in intact cells and tissues.
Authors: Authors: Lee JH, Daugharthy ER, Scheiman J, Kalhor R, Ferrante TC, Terry R, Turczyk BM, Yang JL, Lee HS, Aach J, Zhang K, Church GM.
Nat Protoc
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Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells.
Authors: Authors: Byrne SM, Ortiz L, Mali P, Aach J, Church GM.
Nucleic Acids Res
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Biocontainment of genetically modified organisms by synthetic protein design.
Authors: Authors: Mandell DJ, Lajoie MJ, Mee MT, Takeuchi R, Kuznetsov G, Norville JE, Gregg CJ, Stoddard BL, Church GM.
Nature
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