George Church

George Church, Ph.D.

617-432-7562

Church Lab Website

Publications

Modified bases enable high-efficiency oligonucleotide-mediated allelic replacement via mismatch repair evasion.

Authors: Authors: Wang HH, Xu G, Vonner AJ, Church G.
Nucleic Acids Res 2011-09-01
View full abstract on Pubmed

Precise manipulation of chromosomes in vivo enables genome-wide codon replacement.

Authors: Authors: Isaacs FJ, Carr PA, Wang HH, Lajoie MJ, Sterling B, Kraal L, Tolonen AC, Gianoulis TA, Goodman DB, Reppas NB, Emig CJ, Bang D, Hwang SJ, Jewett MC, Jacobson JM, Church GM.
Science 2011-07-15
View full abstract on Pubmed

Autoantigen discovery with a synthetic human peptidome.

Authors: Authors: Larman HB, Zhao Z, Laserson U, Li MZ, Ciccia A, Gakidis MA, Church GM, Kesari S, Leproust EM, Solimini NL, Elledge SJ.
Nat Biotechnol 2011-05-22
View full abstract on Pubmed

Transcriptional profiling of CD4 T cells identifies distinct subgroups of HIV-1 elite controllers.

Authors: Authors: Vigneault F, Woods M, Buzon MJ, Li C, Pereyra F, Crosby SD, Rychert J, Church G, Martinez-Picado J, Rosenberg ES, Telenti A, Yu XG, Lichterfeld M.
J Virol 2011-03-01
View full abstract on Pubmed

A new dawn for industrial photosynthesis.

Authors: Authors: Robertson DE, Jacobson SA, Morgan F, Berry D, Church GM, Afeyan NB.
Photosynth Res 2011-03-01
View full abstract on Pubmed

Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription.

Authors: Authors: Zhang F, Cong L, Lodato S, Kosuri S, Church GM, Arlotta P.
Nat Biotechnol 2011-02-01
View full abstract on Pubmed

Proteome-wide systems analysis of a cellulosic biofuel-producing microbe.

Authors: Authors: Tolonen AC, Haas W, Chilaka AC, Aach J, Gygi SP, Church GM.
Mol Syst Biol 2011-01-18
View full abstract on Pubmed

RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice.

Authors: Authors: Yu C, Li Y, Holmes A, Szafranski K, Faulkes CG, Coen CW, Buffenstein R, Platzer M, de Magalhães JP, Church GM.
PLoS One 2011-01-01
View full abstract on Pubmed

Multiplexed genome engineering and genotyping methods applications for synthetic biology and metabolic engineering.

Authors: Authors: Wang HH, Church GM.
Methods Enzymol 2011-01-01
View full abstract on Pubmed

Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips.

Authors: Authors: Kosuri S, Eroshenko N, Leproust EM, Super M, Way J, Li JB, Church GM.
Nat Biotechnol 2010-12-01
View full abstract on Pubmed