The amino-acid mutational spectrum of human genetic disease.
From annotated genomes to metabolic flux models and kinetic parameter fitting.
Authors: Authors: Segrè D, Zucker J, Katz J, Lin X, D'haeseleer P, Rindone WP, Kharchenko P, Nguyen DH, Wright MA, Church GM.
OMICS
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OMICS
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Predicting phenotype from patterns of annotation.
Authors: Authors: King OD, Lee JC, Dudley AM, Janse DM, Church GM, Roth FP.
Bioinformatics
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Bioinformatics
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A statistical model for investigating binding probabilities of DNA nucleotide sequences using microarrays.
Analysis of optimality in natural and perturbed metabolic networks.
Authors: Authors: Segrè D, Vitkup D, Church GM.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Genome-wide co-occurrence of promoter elements reveals a cis-regulatory cassette of rRNA transcription motifs in Saccharomyces cerevisiae.
Automated modelling of signal transduction networks.
Authors: Authors: Steffen M, Petti A, Aach J, D'haeseleer P, Church G.
BMC Bioinformatics
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BMC Bioinformatics
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Escherichia coli gene expression responsive to levels of the response regulator EvgA.
An open-source oligomicroarray standard for human and mouse.
Computational discovery of sense-antisense transcription in the human and mouse genomes.