Jeannie T. Lee, M.D., Ph.D.
Phillip A. Sharp Chair in Molecular Biology, Massachusetts General Hospital
Vice Chair of the Department of Genetics, Harvard Medical School
Professor of Genetics and Pathology, Harvard Medical School
Dynamic dosage changes in X-linked transposable elements during mammalian dosage compensation.
Authors: Authors: Wei C, Kesner B, Weissbein U, Wasserzug-Pash P, Das P, Lee JT.
Nat Commun
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Nat Commun
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Jpx RNA controls Xist induction through spatial reorganization of the mouse X-inactivation center.
Authors: Authors: Oh HJ, Das P, Blum R, Kriz AJ, Lee HG, Lee YW, Lee JT.
Dev Cell
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Dev Cell
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Xist RNA binds select autosomal genes and depends on Repeat B to regulate their expression.
An evolving landscape of PRC2-RNA interactions in chromatin regulation.
Authors: Authors: Aguilar R, Rosenberg M, Levy V, Lee JT.
Nat Rev Mol Cell Biol
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Nat Rev Mol Cell Biol
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A biophysical basis for the spreading behavior and limited diffusion of Xist.
Authors: Authors: Ding M, Wang D, Chen H, Kesner B, Grimm NB, Weissbein U, Lappala A, Jiang J, Rivera C, Lou J, Li P, Lee JT.
Cell
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Cell
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7SL RNA and signal recognition particle orchestrate a global cellular response to acute thermal stress.
Authors: Authors: Bujisic B, Lee HG, Xu L, Weissbein U, Rivera C, Topisirovic I, Lee JT.
Nat Commun
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Nat Commun
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Protocol for capturing a full transcriptome from single preimplantation embryos using So-Smart-seq.
Protocol for mapping RNA G-quadruplex for chromatin-bound RNA using d-rG4-seq.
Dosage compensation of transposable elements in mammals.
Authors: Authors: Wei C, Kesner B, Weissbein U, Wasserzug-Pash P, Das P, Lee JT.
bioRxiv
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bioRxiv
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Re-analysis of CLAP data affirms PRC2 as an RNA binding protein.