Jeannie Lee headshot

Jeannie T. Lee, M.D., Ph.D.

Phillip A. Sharp Chair in Molecular Biology, Massachusetts General Hospital
Vice Chair of the Department of Genetics, Harvard Medical School
Professor of Genetics and Pathology, Harvard Medical School
617-726-5943
Lee Lab Website
LINE-1 repeats are a defining feature of the Xce.
Authors: Authors: Jeon Y, Ji F, Das P, Wang PI, Weissbein U, Carrette LLG, Kesner B, Sadreyev R, Lee JT.
Proc Natl Acad Sci U S A
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Deep learning enabled prediction of nuclear lamina-associated chromatin.
Authors: Authors: Das P, Lee JT.
Patterns (N Y)
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SIRT7 regulates dosage compensation and safeguards the female X chromosome.
Authors: Authors: Simonet NG, Thackray JK, Kesner B, Guitart-Solanes A, Serra F, Espinosa-Alcantud M, Lappala A, Marín-Gual L, Marín-García C, Weissbein U, Castelló-García J, Bauer M, Wang D, Rovirosa L, Tischfield J, Serrano L, Payer B, Ruiz-Herrera A, Vazquez BN, Javierre BM, Vaquero A, Lee JT.
Nature
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Dynamic dosage changes in X-linked transposable elements during mammalian dosage compensation.
Authors: Authors: Wei C, Kesner B, Weissbein U, Wasserzug-Pash P, Das P, Lee JT.
Nat Commun
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Jpx RNA controls Xist induction through spatial reorganization of the mouse X-inactivation center.
Authors: Authors: Oh HJ, Das P, Blum R, Kriz AJ, Lee HG, Lee YW, Lee JT.
Dev Cell
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Pharmacologically stabilizing RNA G-quadruplexes in coronavirus genome reduces infectivity.
Authors: Authors: Lee YW, Blum R, Mrozowich T, Bujisic B, Kirby JE, Lee JT.
RNA
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Xist RNA binds select autosomal genes and depends on Repeat B to regulate their expression.
Authors: Authors: Yao S, Jeon Y, Kesner B, Lee JT.
Elife
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An evolving landscape of PRC2-RNA interactions in chromatin regulation.
Authors: Authors: Aguilar R, Rosenberg M, Levy V, Lee JT.
Nat Rev Mol Cell Biol
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A biophysical basis for the spreading behavior and limited diffusion of Xist.
Authors: Authors: Ding M, Wang D, Chen H, Kesner B, Grimm NB, Weissbein U, Lappala A, Jiang J, Rivera C, Lou J, Li P, Lee JT.
Cell
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7SL RNA and signal recognition particle orchestrate a global cellular response to acute thermal stress.
Authors: Authors: Bujisic B, Lee HG, Xu L, Weissbein U, Rivera C, Topisirovic I, Lee JT.
Nat Commun
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