Jeannie T. Lee, M.D., Ph.D.
Phillip A. Sharp Chair in Molecular Biology, Massachusetts General Hospital
Vice Chair of the Department of Genetics, Harvard Medical School
Professor of Genetics and Pathology, Harvard Medical School
An evolving landscape of PRC2-RNA interactions in chromatin regulation.
Authors: Authors: Aguilar R, Rosenberg M, Levy V, Lee JT.
Nat Rev Mol Cell Biol
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Nat Rev Mol Cell Biol
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7SL RNA and signal recognition particle orchestrate a global cellular response to acute thermal stress.
Authors: Authors: Bujisic B, Lee HG, Xu L, Weissbein U, Rivera C, Topisirovic I, Lee JT.
Nat Commun
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Nat Commun
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Protocol for capturing a full transcriptome from single preimplantation embryos using So-Smart-seq.
Protocol for mapping RNA G-quadruplex for chromatin-bound RNA using d-rG4-seq.
Dosage compensation of transposable elements in mammals.
Authors: Authors: Wei C, Kesner B, Weissbein U, Wasserzug-Pash P, Das P, Lee JT.
bioRxiv
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bioRxiv
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Re-analysis of CLAP data affirms PRC2 as an RNA binding protein.
PRC2-RNA interactions: Viewpoint from YongWoo Lee and Jeannie T. Lee.
Xist RNA binds select autosomal genes and depends on Repeat B to regulate their expression.
G-quadruplex folding in Xist RNA antagonizes PRC2 activity for stepwise regulation of X chromosome inactivation.
Imprinted X chromosome inactivation at the gamete-to-embryo transition.