Jeannie Lee headshot
Jeannie T. Lee, M.D., Ph.D.
Professor of Genetics
Targeting Xist with compounds that disrupt RNA structure and X inactivation.
Authors: Authors: Aguilar R, Spencer KB, Kesner B, Rizvi NF, Badmalia MD, Mrozowich T, Mortison JD, Rivera C, Smith GF, Burchard J, Dandliker PJ, Patel TR, Nickbarg EB, Lee JT.
Nature
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Selective Xi reactivation and alternative methods to restore MECP2 function in Rett syndrome.
Authors: Authors: Grimm NB, Lee JT.
Trends Genet
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Denaturing cross-linking immunoprecipitation to identify footprints for RNA-binding proteins.
Authors: Authors: Rosenberg M, Levy V, Maier VK, Kesner B, Blum R, Lee JT.
STAR Protoc
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Jpx RNA regulates CTCF anchor site selection and formation of chromosome loops.
Authors: Authors: Oh HJ, Aguilar R, Kesner B, Lee HG, Kriz AJ, Chu HP, Lee JT.
Cell
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iDRiP for the systematic discovery of proteins bound directly to noncoding RNA.
Authors: Authors: Chu HP, Minajigi A, Chen Y, Morris R, Guh CY, Hsieh YH, Boukhali M, Haas W, Lee JT.
Nat Protoc
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A disproportionate impact of G9a methyltransferase deficiency on the X chromosome.
Authors: Authors: Szanto A, Aguilar R, Kesner B, Blum R, Wang D, Cifuentes-Rojas C, Del Rosario BC, Kis-Toth K, Lee JT.
Genes Dev
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Revisiting the consequences of deleting the X inactivation center.
Authors: Authors: Yin H, Wei C, Lee JT.
Proc Natl Acad Sci U S A
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Balancing cohesin eviction and retention prevents aberrant chromosomal interactions, Polycomb-mediated repression, and X-inactivation.
Authors: Authors: Kriz AJ, Colognori D, Sunwoo H, Nabet B, Lee JT.
Mol Cell
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Xist Repeat A contributes to early recruitment of Polycomb complexes during X-chromosome inactivation.
Authors: Authors: Colognori D, Sunwoo H, Wang D, Wang CY, Lee JT.
Dev Cell
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Motif-driven interactions between RNA and PRC2 are rheostats that regulate transcription elongation.
Authors: Authors: Rosenberg M, Blum R, Kesner B, Aeby E, Garant JM, Szanto A, Lee JT.
Nat Struct Mol Biol
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