G-quadruplex folding in Xist RNA antagonizes PRC2 activity for stepwise regulation of X chromosome inactivation.
Imprinted X chromosome inactivation at the gamete-to-embryo transition.
Variable expression of MECP2, CDKL5, and FMR1 in the human brain: Implications for gene restorative therapies.
Site-specific R-loops induce CGG repeat contraction and fragile X gene reactivation.
Authors: Authors: Lee HG, Imaichi S, Kraeutler E, Aguilar R, Lee YW, Sheridan SD, Lee JT.
Cell
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Cell
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Targeting RNA with small molecules: lessons learned from Xist RNA.
Targeting Xist with compounds that disrupt RNA structure and X inactivation.
Authors: Authors: Aguilar R, Spencer KB, Kesner B, Rizvi NF, Badmalia MD, Mrozowich T, Mortison JD, Rivera C, Smith GF, Burchard J, Dandliker PJ, Patel TR, Nickbarg EB, Lee JT.
Nature
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Nature
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Selective Xi reactivation and alternative methods to restore MECP2 function in Rett syndrome.
Denaturing cross-linking immunoprecipitation to identify footprints for RNA-binding proteins.
Authors: Authors: Rosenberg M, Levy V, Maier VK, Kesner B, Blum R, Lee JT.
STAR Protoc
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STAR Protoc
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Jpx RNA regulates CTCF anchor site selection and formation of chromosome loops.
Authors: Authors: Oh HJ, Aguilar R, Kesner B, Lee HG, Kriz AJ, Chu HP, Lee JT.
Cell
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Cell
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A disproportionate impact of G9a methyltransferase deficiency on the X chromosome.
Authors: Authors: Szanto A, Aguilar R, Kesner B, Blum R, Wang D, Cifuentes-Rojas C, Del Rosario BC, Kis-Toth K, Lee JT.
Genes Dev
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Genes Dev
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