Jeannie T. Lee, M.D., Ph.D.
Phillip A. Sharp Chair in Molecular Biology, Massachusetts General Hospital
Vice Chair of the Department of Genetics, Harvard Medical School
Professor of Genetics and Pathology, Harvard Medical School
Regulatory interactions between RNA and polycomb repressive complex 2.
Authors: Authors: Cifuentes-Rojas C, Hernandez AJ, Sarma K, Lee JT.
Mol Cell
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Mol Cell
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Long noncoding RNAs: fresh perspectives into the RNA world.
Coupling of X-chromosome reactivation with the pluripotent stem cell state.
Tsix RNA and the germline factor, PRDM14, link X reactivation and stem cell reprogramming.
Authors: Authors: Payer B, Rosenberg M, Yamaji M, Yabuta Y, Koyanagi-Aoi M, Hayashi K, Yamanaka S, Saitou M, Lee JT.
Mol Cell
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Mol Cell
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High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation.
Authors: Authors: Simon MD, Pinter SF, Fang R, Sarma K, Rutenberg-Schoenberg M, Bowman SK, Kesner BA, Maier VK, Kingston RE, Lee JT.
Nature
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Nature
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Guided by RNAs: X-inactivation as a model for lncRNA function.
Jpx RNA activates Xist by evicting CTCF.
Authors: Authors: Sun S, Del Rosario BC, Szanto A, Ogawa Y, Jeon Y, Lee JT.
Cell
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Cell
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Bimodal quantitative relationships between histone modifications for X-linked and autosomal loci.
Authors: Authors: Sadreyev RI, Yildirim E, Pinter SF, Lee JT.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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RNA in the loop.
X-inactivation, imprinting, and long noncoding RNAs in health and disease.