
Jeannie T. Lee, M.D., Ph.D.
Phillip A. Sharp Chair in Molecular Biology, Massachusetts General Hospital
Vice Chair of the Department of Genetics, Harvard Medical School
Professor of Genetics and Pathology, Harvard Medical School
Long noncoding RNAs: past, present, and future.
Xist RNA is a potent suppressor of hematologic cancer in mice.
Authors: Authors: Yildirim E, Kirby JE, Brown DE, Mercier FE, Sadreyev RI, Scadden DT, Lee JT.
Cell
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Cell
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X chromosome inactivation and epigenetic responses to cellular reprogramming.
Authors: Authors: Lessing D, Anguera MC, Lee JT.
Annu Rev Genomics Hum Genet
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Annu Rev Genomics Hum Genet
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Epigenetic regulation by long noncoding RNAs.
ALKBH1 is a histone H2A dioxygenase involved in neural differentiation.
Authors: Authors: Ougland R, Lando D, Jonson I, Dahl JA, Moen MN, Nordstrand LM, Rognes T, Lee JT, Klungland A, Kouzarides T, Larsen E.
Stem Cells
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Stem Cells
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An ex vivo model for imprinting: mutually exclusive binding of Cdx2 and Oct4 as a switch for imprinted and random X-inactivation.
Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations.
Authors: Authors: Pinter SF, Sadreyev RI, Yildirim E, Jeon Y, Ohsumi TK, Borowsky M, Lee JT.
Genome Res
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Genome Res
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Molecular signatures of human induced pluripotent stem cells highlight sex differences and cancer genes.
Authors: Authors: Anguera MC, Sadreyev R, Zhang Z, Szanto A, Payer B, Sheridan SD, Kwok S, Haggarty SJ, Sur M, Alvarez J, Gimelbrant A, Mitalipova M, Kirby JE, Lee JT.
Cell Stem Cell
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Cell Stem Cell
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New and Xisting regulatory mechanisms of X chromosome inactivation.
X-chromosome hyperactivation in mammals via nonlinear relationships between chromatin states and transcription.
Authors: Authors: Yildirim E, Sadreyev RI, Pinter SF, Lee JT.
Nat Struct Mol Biol
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Nat Struct Mol Biol
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