Jeannie T. Lee, M.D., Ph.D.
Phillip A. Sharp Chair in Molecular Biology, Massachusetts General Hospital
Vice Chair of the Department of Genetics, Harvard Medical School
Professor of Genetics and Pathology, Harvard Medical School
Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus.
Authors: Authors: Lindroth AM, Park YJ, McLean CM, Dokshin GA, Persson JM, Herman H, Pasini D, Miró X, Donohoe ME, Lee JT, Helin K, Soloway PD.
PLoS Genet
View full abstract on Pubmed
PLoS Genet
View full abstract on Pubmed
Higher order chromatin structure at the X-inactivation center via looping DNA.
Intersection of the RNA interference and X-inactivation pathways.
New twists in X-chromosome inactivation.
X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells.
Authors: Authors: Silva SS, Rowntree RK, Mekhoubad S, Lee JT.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Proc Natl Acad Sci U S A
View full abstract on Pubmed
X chromosome dosage compensation: how mammals keep the balance.
Dosage compensation in the mouse balances up-regulation and silencing of X-linked genes.
Authors: Authors: Lin H, Gupta V, Vermilyea MD, Falciani F, Lee JT, O'Neill LP, Turner BM.
PLoS Biol
View full abstract on Pubmed
PLoS Biol
View full abstract on Pubmed
Evidence that homologous X-chromosome pairing requires transcription and Ctcf protein.
Sex chromosome silencing in the marsupial male germ line.
Authors: Authors: Namekawa SH, VandeBerg JL, McCarrey JR, Lee JT.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Perinucleolar targeting of the inactive X during S phase: evidence for a role in the maintenance of silencing.