Jeannie T. Lee, M.D., Ph.D.
Phillip A. Sharp Chair in Molecular Biology, Massachusetts General Hospital
Vice Chair of the Department of Genetics, Harvard Medical School
Professor of Genetics and Pathology, Harvard Medical School
Molecular biology: Complicity of gene and pseudogene.
Molecular links between X-inactivation and autosomal imprinting: X-inactivation as a driving force for the evolution of imprinting?
Xite, X-inactivation intergenic transcription elements that regulate the probability of choice.
Characterization and quantitation of differential Tsix transcripts: implications for Tsix function.
Homozygous Tsix mutant mice reveal a sex-ratio distortion and revert to random X-inactivation.
X-chromosome inactivation and the search for chromosome-wide silencers.
CTCF, a candidate trans-acting factor for X-inactivation choice.
Authors: Authors: Chao W, Huynh KD, Spencer RJ, Davidow LS, Lee JT.
Science
View full abstract on Pubmed
Science
View full abstract on Pubmed
Is X-chromosome inactivation a homology effect?
Disruption of imprinted X inactivation by parent-of-origin effects at Tsix.
Targeted mutagenesis of Tsix leads to nonrandom X inactivation.