Jeannie Lee headshot

Jeannie T. Lee, M.D., Ph.D.

Phillip A. Sharp Chair in Molecular Biology, Massachusetts General Hospital
Vice Chair of the Department of Genetics, Harvard Medical School
Professor of Genetics and Pathology, Harvard Medical School
617-726-5943
Lee Lab Website
Denaturing cross-linking immunoprecipitation to identify footprints for RNA-binding proteins.
Authors: Authors: Rosenberg M, Levy V, Maier VK, Kesner B, Blum R, Lee JT.
STAR Protoc
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Jpx RNA regulates CTCF anchor site selection and formation of chromosome loops.
Authors: Authors: Oh HJ, Aguilar R, Kesner B, Lee HG, Kriz AJ, Chu HP, Lee JT.
Cell
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Revealing RCOR2 as a regulatory component of nuclear speckles.
Authors: Authors: Rivera C, Verbel-Vergara D, Arancibia D, Lappala A, González M, Guzmán F, Merello G, Lee JT, Andrés ME.
Epigenetics Chromatin
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Four-dimensional chromosome reconstruction elucidates the spatiotemporal reorganization of the mammalian X chromosome.
Authors: Authors: Lappala A, Wang CY, Kriz A, Michalk H, Tan K, Lee JT, Sanbonmatsu KY.
Proc Natl Acad Sci U S A
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A disproportionate impact of G9a methyltransferase deficiency on the X chromosome.
Authors: Authors: Szanto A, Aguilar R, Kesner B, Blum R, Wang D, Cifuentes-Rojas C, Del Rosario BC, Kis-Toth K, Lee JT.
Genes Dev
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iDRiP for the systematic discovery of proteins bound directly to noncoding RNA.
Authors: Authors: Chu HP, Minajigi A, Chen Y, Morris R, Guh CY, Hsieh YH, Boukhali M, Haas W, Lee JT.
Nat Protoc
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Revisiting the consequences of deleting the X inactivation center.
Authors: Authors: Yin H, Wei C, Lee JT.
Proc Natl Acad Sci U S A
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Balancing cohesin eviction and retention prevents aberrant chromosomal interactions, Polycomb-mediated repression, and X-inactivation.
Authors: Authors: Kriz AJ, Colognori D, Sunwoo H, Nabet B, Lee JT.
Mol Cell
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Xist Repeat A contributes to early recruitment of Polycomb complexes during X-chromosome inactivation.
Authors: Authors: Colognori D, Sunwoo H, Wang D, Wang CY, Lee JT.
Dev Cell
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Motif-driven interactions between RNA and PRC2 are rheostats that regulate transcription elongation.
Authors: Authors: Rosenberg M, Blum R, Kesner B, Aeby E, Garant JM, Szanto A, Lee JT.
Nat Struct Mol Biol
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