Jeannie T. Lee

Jeannie T. Lee, M.D., Ph.D.

Professor of Genetics

617-726-5943

Lee Lab Website

Publications

The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis.

Authors: Authors: Lewandowski JP, Lee JC, Hwang T, Sunwoo H, Goldstein JM, Groff AF, Chang NP, Mallard W, Williams A, Henao-Meija J, Flavell RA, Lee JT, Gerhardinger C, Wagers AJ, Rinn JL.
Nat Commun 2019-11-13
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Aberrant mitochondrial function in patient-derived neural cells from CDKL5 deficiency disorder and Rett syndrome.

Authors: Authors: Jagtap S, Thanos JM, Fu T, Wang J, Lalonde J, Dial TO, Feiglin A, Chen J, Kohane I, Lee JT, Sheridan SD, Perlis RH.
Hum Mol Genet 2019-11-01
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Role of the Chromosome Architectural Factor SMCHD1 in X-Chromosome Inactivation, Gene Regulation, and Disease in Humans.

Authors: Authors: Wang CY, Brand H, Shaw ND, Talkowski ME, Lee JT.
Genetics 2019-10-01
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PRC1 collaborates with SMCHD1 to fold the X-chromosome and spread Xist RNA between chromosome compartments.

Authors: Authors: Wang CY, Colognori D, Sunwoo H, Wang D, Lee JT.
Nat Commun 2019-07-03
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Xist Deletional Analysis Reveals an Interdependency between Xist RNA and Polycomb Complexes for Spreading along the Inactive X.

Authors: Authors: Colognori D, Sunwoo H, Kriz AJ, Wang CY, Lee JT.
Mol Cell 2019-04-04
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Exploration of CTCF post-translation modifications uncovers Serine-224 phosphorylation by PLK1 at pericentric regions during the G2/M transition.

Authors: Authors: Del Rosario BC, Kriz AJ, Del Rosario AM, Anselmo A, Fry CJ, White FM, Sadreyev RI, Lee JT.
Elife 2019-01-24
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Megadomains and superloops form dynamically but are dispensable for X-chromosome inactivation and gene escape.

Authors: Authors: Froberg JE, Pinter SF, Kriz AJ, Jégu T, Lee JT.
Nat Commun 2018-11-27
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Multiple Histone Methyl-Lysine Readers Ensure Robust Development and Germline Immortality in Caenorhabditis elegans.

Authors: Authors: Saltzman AL, Soo MW, Aram R, Lee JT.
Genetics 2018-11-01
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Loss of H3K27me3 Imprinting in Somatic Cell Nuclear Transfer Embryos Disrupts Post-Implantation Development.

Authors: Authors: Matoba S, Wang H, Jiang L, Lu F, Iwabuchi KA, Wu X, Inoue K, Yang L, Press W, Lee JT, Ogura A, Shen L, Zhang Y.
Cell Stem Cell 2018-09-06
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Tsix-Mecp2 female mouse model for Rett syndrome reveals that low-level MECP2 expression extends life and improves neuromotor function.

Authors: Authors: Carrette LLG, Blum R, Ma W, Kelleher RJ, Lee JT.
Proc Natl Acad Sci U S A 2018-08-07
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