Joel Hirschhorn headshot

Joel Naom Hirschhorn, M.D., Ph.D.

Chief of the Division of Endocrinology, Boston Children's Hospital
Concordia Professor of Pediatrics and Professor of Genetics, Harvard Medical School.
617-919-2129
Hirschhorn Lab Website
Genomewide linkage analysis of stature in multiple populations reveals several regions with evidence of linkage to adult height.
Authors: Authors: Hirschhorn JN, Lindgren CM, Daly MJ, Kirby A, Schaffner SF, Burtt NP, Altshuler D, Parker A, Rioux JD, Platko J, Gaudet D, Hudson TJ, Groop LC, Lander ES.
Am J Hum Genet
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SBE-TAGS: an array-based method for efficient single-nucleotide polymorphism genotyping.
Authors: Authors: Hirschhorn JN, Sklar P, Lindblad-Toh K, Lim YM, Ruiz-Gutierrez M, Bolk S, Langhorst B, Schaffner S, Winchester E, Lander ES.
Proc Natl Acad Sci U S A
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The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes.
Authors: Authors: Altshuler D, Hirschhorn JN, Klannemark M, Lindgren CM, Vohl MC, Nemesh J, Lane CR, Schaffner SF, Bolk S, Brewer C, Tuomi T, Gaudet D, Hudson TJ, Daly M, Groop L, Lander ES.
Nat Genet
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Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse.
Authors: Authors: Lindblad-Toh K, Winchester E, Daly MJ, Wang DG, Hirschhorn JN, Laviolette JP, Ardlie K, Reich DE, Robinson E, Sklar P, Shah N, Thomas D, Fan JB, Gingeras T, Warrington J, Patil N, Hudson TJ, Lander ES.
Nat Genet
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Upsetting the balance: VGF and the regulation of body weight.
Authors: Authors: Altshuler D, Hirschhorn JN.
Neuron
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A new class of histone H2A mutations in Saccharomyces cerevisiae causes specific transcriptional defects in vivo.
Authors: Authors: Hirschhorn JN, Bortvin AL, Ricupero-Hovasse SL, Winston F.
Mol Cell Biol
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Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure.
Authors: Authors: Hirschhorn JN, Brown SA, Clark CD, Winston F.
Genes Dev
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SPT3 is required for normal levels of a-factor and alpha-factor expression in Saccharomyces cerevisiae.
Authors: Authors: Hirschhorn JN, Winston F.
Mol Cell Biol
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Nature
Authors: Authors: Post-translational control of beige fat biogenesis by PRDM16 stabilization
2022 09; 609(7925):151-158.
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Am J Hum Genet
Authors: Authors: A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
2022 08 04; 109(8):1366-1387.
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