Jonathan Seidman headshot

Jonathan G. Seidman, Ph.D.

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
617-432-7830
Seidman Lab Website
Early remodeling of repolarizing K+ currents in the aMHC403/+ mouse model of familial hypertrophic cardiomyopathy.
Authors: Authors: Hueneke R, Adenwala A, Mellor RL, Seidman JG, Seidman CE, Nerbonne JM.
J Mol Cell Cardiol
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A Novel Role for CSRP1 in a Lebanese Family with Congenital Cardiac Defects.
Authors: Authors: Kamar A, Fahed AC, Shibbani K, El-Hachem N, Bou-Slaiman S, Arabi M, Kurban M, Seidman JG, Seidman CE, Haidar R, Baydoun E, Nemer G, Bitar F.
Front Genet
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Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy.
Authors: Authors: Esslinger U, Garnier S, Korniat A, Proust C, Kararigas G, Müller-Nurasyid M, Empana JP, Morley MP, Perret C, Stark K, Bick AG, Prasad SK, Kriebel J, Li J, Tiret L, Strauch K, O'Regan DP, Marguiles KB, Seidman JG, Boutouyrie P, Lacolley P, Jouven X, Hengstenberg C, Komajda M, Hakonarson H, Isnard R, Arbustini E, Grallert H, Cook SA, Seidman CE, Regitz-Zagrosek V, Cappola TP, Charron P, Cambien F, Villard E.
PLoS One
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Titin-truncating variants affect heart function in disease cohorts and the general population.
Authors: Authors: Schafer S, de Marvao A, Adami E, Fiedler LR, Ng B, Khin E, Rackham OJ, van Heesch S, Pua CJ, Kui M, Walsh R, Tayal U, Prasad SK, Dawes TJ, Ko NS, Sim D, Chan LL, Chin CW, Mazzarotto F, Barton PJ, Kreuchwig F, de Kleijn DP, Totman T, Biffi C, Tee N, Rueckert D, Schneider V, Faber A, Regitz-Zagrosek V, Seidman JG, Seidman CE, Linke WA, Kovalik JP, O'Regan D, Ware JS, Hubner N, Cook SA.
Nat Genet
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The Long Noncoding RNA Landscape of the Ischemic Human Left Ventricle.
Authors: Authors: Saddic LA, Sigurdsson MI, Chang TW, Mazaika E, Heydarpour M, Shernan SK, Seidman CE, Seidman JG, Aranki SF, Body SC, Muehlschlegel JD.
Circ Cardiovasc Genet
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Clinical and Mechanistic Insights Into the Genetics of Cardiomyopathy.
Authors: Authors: Burke MA, Cook SA, Seidman JG, Seidman CE.
J Am Coll Cardiol
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Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.
Authors: Authors: Hinson JT, Chopra A, Lowe A, Sheng CC, Gupta RM, Kuppusamy R, O'Sullivan J, Rowe G, Wakimoto H, Gorham J, Burke MA, Zhang K, Musunuru K, Gerszten RE, Wu SM, Chen CS, Seidman JG, Seidman CE.
Cell Rep
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Preparation of rAAV9 to Overexpress or Knockdown Genes in Mouse Hearts.
Authors: Authors: Ding J, Lin ZQ, Jiang JM, Seidman CE, Seidman JG, Pu WT, Wang DZ.
J Vis Exp
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Allele-specific expression in the human heart and its application to postoperative atrial fibrillation and myocardial ischemia.
Authors: Authors: Sigurdsson MI, Saddic L, Heydarpour M, Chang TW, Shekar P, Aranki S, Couper GS, Shernan SK, Seidman JG, Body SC, Muehlschlegel JD.
Genome Med
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THSD1 (Thrombospondin Type 1 Domain Containing Protein 1) Mutation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage.
Authors: Authors: Santiago-Sim T, Fang X, Hennessy ML, Nalbach SV, DePalma SR, Lee MS, Greenway SC, McDonough B, Hergenroeder GW, Patek KJ, Colosimo SM, Qualmann KJ, Hagan JP, Milewicz DM, MacRae CA, Dymecki SM, Seidman CE, Seidman JG, Kim DH.
Stroke
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