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Jonathan G. Seidman, Ph.D.

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
617-432-7830
Seidman Lab Website
Loss of RNA expression and allele-specific expression associated with congenital heart disease.
Authors: Authors: McKean DM, Homsy J, Wakimoto H, Patel N, Gorham J, DePalma SR, Ware JS, Zaidi S, Ma W, Patel N, Lifton RP, Chung WK, Kim R, Shen Y, Brueckner M, Goldmuntz E, Sharp AJ, Seidman CE, Gelb BD, Seidman JG.
Nat Commun
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Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm.
Authors: Authors: Nadadur RD, Broman MT, Boukens B, Mazurek SR, Yang X, van den Boogaard M, Bekeny J, Gadek M, Ward T, Zhang M, Qiao Y, Martin JF, Seidman CE, Seidman J, Christoffels V, Efimov IR, McNally EM, Weber CR, Moskowitz IP.
Sci Transl Med
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Detection of Cell Proliferation Markers by Immunofluorescence Staining and Microscopy Imaging in Paraffin-Embedded Tissue Sections.
Authors: Authors: Eminaga S, Teekakirikul P, Seidman CE, Seidman JG.
Curr Protoc Mol Biol
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AAV9 Delivery of shRNA to the Mouse Heart.
Authors: Authors: Wakimoto H, Seidman JG, Foo RS, Jiang J.
Curr Protoc Mol Biol
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Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies.
Authors: Authors: Ware JS, Seidman JG, Arany Z.
N Engl J Med
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A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy.
Authors: Authors: Davis J, Davis LC, Correll RN, Makarewich CA, Schwanekamp JA, Moussavi-Harami F, Wang D, York AJ, Wu H, Houser SR, Seidman CE, Seidman JG, Regnier M, Metzger JM, Wu JC, Molkentin JD.
Cell
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Molecular profiling of dilated cardiomyopathy that progresses to heart failure.
Authors: Authors: Burke MA, Chang S, Wakimoto H, Gorham JM, Conner DA, Christodoulou DC, Parfenov MG, DePalma SR, Eminaga S, Konno T, Seidman JG, Seidman CE.
JCI Insight
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Pillars Article: Identification of a Putative Second T-cell Receptor. Nature. 1986. 322: 145-149.
Authors: Authors: Brenner MB, McLean J, Dialynas DP, Strominger JL, Smith JA, Owen FL, Seidman JG, Ip S, Rosen F, Krangel MS.
J Immunol
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The Muscle-Bound Heart.
Authors: Authors: Refaat MM, Fahed AC, Hassanieh S, Hotait M, Arabi M, Skouri H, Seidman JG, Seidman CE, Bitar FF, Nemer G.
Card Electrophysiol Clin
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A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice.
Authors: Authors: Green EM, Wakimoto H, Anderson RL, Evanchik MJ, Gorham JM, Harrison BC, Henze M, Kawas R, Oslob JD, Rodriguez HM, Song Y, Wan W, Leinwand LA, Spudich JA, McDowell RS, Seidman JG, Seidman CE.
Science
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