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Jonathan G. Seidman, Ph.D.

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
617-432-7830
Seidman Lab Website
Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting.
Authors: Authors: Fox AA, Collard CD, Shernan SK, Seidman CE, Seidman JG, Liu KY, Muehlschlegel JD, Perry TE, Aranki SF, Lange C, Herman DS, Meitinger T, Lichtner P, Body SC.
Anesthesiology
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Clinical outcome and phenotypic expression in LAMP2 cardiomyopathy.
Authors: Authors: Maron BJ, Roberts WC, Arad M, Haas TS, Spirito P, Wright GB, Almquist AK, Baffa JM, Saul JP, Ho CY, Seidman J, Seidman CE.
JAMA
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Genomewide linkage in a large Caucasian family maps a new locus for intracranial aneurysms to chromosome 13q.
Authors: Authors: Santiago-Sim T, Depalma SR, Ju KL, McDonough B, Seidman CE, Seidman JG, Kim DH.
Stroke
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Pheochromocytoma-induced cardiomyopathy is modulated by the synergistic effects of cell-secreted factors.
Authors: Authors: Mobine HR, Baker AB, Wang L, Wakimoto H, Jacobsen KC, Seidman CE, Seidman JG, Edelman ER.
Circ Heart Fail
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Alterations of phospholamban function can exhibit cardiotoxic effects independent of excessive sarcoplasmic reticulum Ca2+-ATPase inhibition.
Authors: Authors: Schmitt JP, Ahmad F, Lorenz K, Hein L, Schulz S, Asahi M, Maclennan DH, Seidman CE, Seidman JG, Lohse MJ.
Circulation
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E2F3 plays an essential role in cardiac development and function.
Authors: Authors: King JC, Moskowitz IP, Burgon PG, Ahmad F, Stone JR, Seidman JG, Lees JA.
Cell Cycle
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Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish.
Authors: Authors: Wang L, Sewell WF, Kim SD, Shin JT, MacRae CA, Zon LI, Seidman JG, Seidman CE.
Development
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The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy.
Authors: Authors: Ahmad F, Banerjee SK, Lage ML, Huang XN, Smith SH, Saba S, Rager J, Conner DA, Janczewski AM, Tobita K, Tinney JP, Moskowitz IP, Perez-Atayde AR, Keller BB, Mathier MA, Shroff SG, Seidman CE, Seidman JG.
PLoS One
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Shared genetic causes of cardiac hypertrophy in children and adults.
Authors: Authors: Morita H, Rehm HL, Menesses A, McDonough B, Roberts AE, Kucherlapati R, Towbin JA, Seidman JG, Seidman CE.
N Engl J Med
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Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy.
Authors: Authors: Tsoutsman T, Kelly M, Ng DC, Tan JE, Tu E, Lam L, Bogoyevitch MA, Seidman CE, Seidman JG, Semsarian C.
Circulation
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