Jonathan Seidman headshot

Jonathan G. Seidman, Ph.D.

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
617-432-7830
Seidman Lab Website
Targeted ablation of the murine alpha-tropomyosin gene.
Authors: Authors: Blanchard EM, Iizuka K, Christe M, Conner DA, Geisterfer-Lowrance A, Schoen FJ, Maughan DW, Seidman CE, Seidman JG.
Circ Res
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Characterization of endoglin and identification of novel mutations in hereditary hemorrhagic telangiectasia.
Authors: Authors: Shovlin CL, Hughes JM, Scott J, Seidman CE, Seidman JG.
Am J Hum Genet
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Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome.
Authors: Authors: Bamshad M, Lin RC, Law DJ, Watkins WC, Krakowiak PA, Moore ME, Franceschini P, Lala R, Holmes LB, Gebuhr TC, Bruneau BG, Schinzel A, Seidman JG, Seidman CE, Jorde LB.
Nat Genet
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Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function.
Authors: Authors: Golitsina N, An Y, Greenfield NJ, Thierfelder L, Iizuka K, Seidman JG, Seidman CE, Lehrer SS, Hitchcock-DeGregori SE.
Biochemistry
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Cao-sensing receptor (CaR)-mediated activation of K+ channels is blunted in CaR gene-deficient mouse neurons.
Authors: Authors: Vassilev PM, Ho-Pao CL, Kanazirska MP, Ye C, Hong K, Seidman CE, Seidman JG, Brown EM.
Neuroreport
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Various types of hereditary inclusion body myopathies map to chromosome 9p1-q1.
Authors: Authors: Argov Z, Tiram E, Eisenberg I, Sadeh M, Seidman CE, Seidman JG, Karpati G, Mitrani-Rosenbaum S.
Ann Neurol
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Cytoskeletal changes in the brains of mice lacking calcineurin A alpha.
Authors: Authors: Kayyali US, Zhang W, Yee AG, Seidman JG, Potter H.
J Neurochem
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Amyloid-beta proteins activate Ca(2+)-permeable channels through calcium-sensing receptors.
Authors: Authors: Ye C, Ho-Pao CL, Kanazirska M, Quinn S, Rogers K, Seidman CE, Seidman JG, Brown EM, Vassilev PM.
J Neurosci Res
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Clinical features of hypertrophic cardiomyopathy caused by mutation of a "hot spot" in the alpha-tropomyosin gene.
Authors: Authors: Coviello DA, Maron BJ, Spirito P, Watkins H, Vosberg HP, Thierfelder L, Schoen FJ, Seidman JG, Seidman CE.
J Am Coll Cardiol
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Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophic cardiomyopathy mice.
Authors: Authors: Berul CI, Christe ME, Aronovitz MJ, Seidman CE, Seidman JG, Mendelsohn ME.
J Clin Invest
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