Jonathan Seidman headshot

Jonathan G. Seidman, Ph.D.

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
617-432-7830
Seidman Lab Website
Mutations in cardiac myosin heavy chain genes cause familial hypertrophic cardiomyopathy.
Authors: Authors: Seidman CE, Seidman JG.
Mol Biol Med
View full abstract on Pubmed
Alloreactive lymphocytes from T cell receptor (beta-chain) transgenic mice do not mediate a graft-versus-host reaction.
Authors: Authors: Rimm IJ, Ghayur T, Gasser DL, Rosenkrantz K, Burakoff SJ, Seidman JG, Ferrara JL.
J Immunol
View full abstract on Pubmed
A molecular basis for familial hypertrophic cardiomyopathy: a beta cardiac myosin heavy chain gene missense mutation.
Authors: Authors: Geisterfer-Lowrance AA, Kass S, Tanigawa G, Vosberg HP, McKenna W, Seidman CE, Seidman JG.
Cell
View full abstract on Pubmed
A molecular basis for familial hypertrophic cardiomyopathy: an alpha/beta cardiac myosin heavy chain hybrid gene.
Authors: Authors: Tanigawa G, Jarcho JA, Kass S, Solomon SD, Vosberg HP, Seidman JG, Seidman CE.
Cell
View full abstract on Pubmed
Heavy and light chain contributions to antigen binding in an anti-digoxin chain recombinant antibody produced by transfection of cloned anti-digoxin antibody genes.
Authors: Authors: Near RI, Ng SC, Mudgett-Hunter M, Hudson NW, Margolies MN, Seidman JG, Haber E, Jacobson MA.
Mol Immunol
View full abstract on Pubmed
Familial hypertrophic cardiomyopathy is a genetically heterogeneous disease.
Authors: Authors: Solomon SD, Jarcho JA, McKenna W, Geisterfer-Lowrance A, Germain R, Salerni R, Seidman JG, Seidman CE.
J Clin Invest
View full abstract on Pubmed
cis modification of the steroid 21-hydroxylase gene prevents its expression in the Y1 mouse adrenocortical tumor cell line.
Authors: Authors: Szyf M, Milstone DS, Schimmer BP, Parker KL, Seidman JG.
Mol Endocrinol
View full abstract on Pubmed
Shared human T cell receptor V beta usage to immunodominant regions of myelin basic protein.
Authors: Authors: Wucherpfennig KW, Ota K, Endo N, Seidman JG, Rosenzweig A, Weiner HL, Hafler DA.
Science
View full abstract on Pubmed
Gamma-delta T cells in Chediak-Higashi syndrome.
Authors: Authors: Holcombe RF, van de Griend R, Ang SL, Bolhuis RL, Seidman JG.
Acta Haematol
View full abstract on Pubmed
The G protein alpha o subunit alters morphology, growth kinetics, and phospholipid metabolism of somatic cells.
Authors: Authors: Bloch DB, Bonventre JV, Neer EJ, Seidman JG.
Mol Cell Biol
View full abstract on Pubmed