Jonathan G. Seidman, Ph.D.
Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
Mouse beta 2-microglobulin cDNA clones: a screening procedure for cDNA clones corresponding to rare mRNAs.
Authors: Authors: Parnes JR, Velan B, Felsenfeld A, Ramanathan L, Ferrini U, Appella E, Seidman JG.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Recombination events that activate, diversify, and delete immunoglobulin genes.
Authors: Authors: Leder P, Max EE, Seidman JG, Kwan SP, Scharff M, Nau M, Norman B.
Cold Spring Harb Symp Quant Biol
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Cold Spring Harb Symp Quant Biol
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Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments.
Authors: Authors: Hieter PA, Max EE, Seidman JG, Maizel JV, Leder P.
Cell
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Cell
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Variation in the crossover point of kappa immunoglobulin gene V-J recombination: evidence from a cryptic gene.
Immunoglobulin V/J recombination is accompanied by deletion of joining site and variable region segments.
Authors: Authors: Seidman JG, Nau MM, Norman B, Kwan SP, Scharff M, Leder P.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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A mutant immunoglobulin light chain is formed by aberrant DNA- and RNA-splicing events.
Messenger RNA coding for the deleted heavy chain of mouse myeloma MOPC 47A immunoglobulin.
Authors: Authors: Robinson EA, Ferrini U, Seidman JG, Appella E.
J Biol Chem
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J Biol Chem
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Immunoglobulin gamma 1 heavy chain gene: structural gene sequences cloned in a bacterial plasmid.
Authors: Authors: Obata M, Yamawaki-Kataoka Y, Takahashi N, Kataoka T, Shimizu A, Mano Y, Seidman JG, Peterlin BM, Leder P, Honjo T.
Gene
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Gene
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Transcription of mouse kappa chain genes: implications for allelic exclusion.
Authors: Authors: Perry RP, Kelley DE, Coleclough C, Seidman JG, Leder P, Tonegawa S, Matthyssens G, Weigert M.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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A kappa-immunoglobulin gene is formed by site-specific recombination without further somatic mutation.