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Jonathan G. Seidman, Ph.D.

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
617-432-7830
Seidman Lab Website
Advances in the Genetic Basis and Pathogenesis of Sarcomere Cardiomyopathies.
Authors: Authors: Yotti R, Seidman CE, Seidman JG.
Annu Rev Genomics Hum Genet
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ORE Identifies Extreme Expression Effects Enriched for Rare Variants.
Authors: Authors: Richter F, Hoffman GE, Manheimer KB, Patel N, Sharp AJ, McKean D, Morton SU, DePalma S, Gorham J, Kitaygorodksy A, Porter GA, Giardini A, Shen Y, Chung WK, Seidman JG, Seidman CE, Schadt EE, Gelb BD.
Bioinformatics
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Activin type II receptor signaling in cardiac aging and heart failure.
Authors: Authors: Roh JD, Hobson R, Chaudhari V, Quintero P, Yeri A, Benson M, Xiao C, Zlotoff D, Bezzerides V, Houstis N, Platt C, Damilano F, Lindman BR, Elmariah S, Biersmith M, Lee SJ, Seidman CE, Seidman JG, Gerszten RE, Lach-Trifilieff E, Glass DJ, Rosenzweig A.
Sci Transl Med
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Genome sequencing as a first-line genetic test in familial dilated cardiomyopathy.
Authors: Authors: Minoche AE, Horvat C, Johnson R, Gayevskiy V, Morton SU, Drew AP, Woo K, Statham AL, Lundie B, Bagnall RD, Ingles J, Semsarian C, Seidman JG, Seidman CE, Dinger ME, Cowley MJ, Fatkin D.
Genet Med
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Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin.
Authors: Authors: Toepfer CN, Wakimoto H, Garfinkel AC, McDonough B, Liao D, Jiang J, Tai AC, Gorham JM, Lunde IG, Lun M, Lynch TL, McNamara JW, Sadayappan S, Redwood CS, Watkins HC, Seidman JG, Seidman CE.
Sci Transl Med
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Sex differences in gene expression in response to ischemia in the human left ventricular myocardium.
Authors: Authors: Stone G, Choi A, Oliva M, Gorham J, Heydarpour M, Seidman CE, Seidman JG, Aranki SF, Body SC, Carey VJ, Raby BA, Stranger BE, Muehlschlegel JD.
Hum Mol Genet
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A gene-centric strategy for identifying disease-causing rare variants in dilated cardiomyopathy.
Authors: Authors: Horvat C, Johnson R, Lam L, Munro J, Mazzarotto F, Roberts AM, Herman DS, Parfenov M, Haghighi A, McDonough B, DePalma SR, Keogh AM, Macdonald PS, Hayward CS, Roberts A, Barton PJR, Felkin LE, Giannoulatou E, Cook SA, Seidman JG, Seidman CE, Fatkin D.
Genet Med
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Genetic profiling of fatty acid desaturase polymorphisms identifies patients who may benefit from high-dose omega-3 fatty acids in cardiac remodeling after acute myocardial infarction-Post-hoc analysis from the OMEGA-REMODEL randomized controlled trial.
Authors: Authors: Kwong RY, Heydari B, Ge Y, Abdullah S, Fujikura K, Kaneko K, Harris WS, Jerosch-Herold M, Antman EM, Seidman JG, Pfeffer MA.
PLoS One
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The Transcriptional Signature of Growth in Human Fetal Aortic Valve Development.
Authors: Authors: Gottlieb Sen D, Halu A, Razzaque A, Gorham JM, Hartnett J, Seidman JG, Aikawa E, Seidman CE.
Ann Thorac Surg
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Molecular Genetics of Lidocaine-Containing Cardioplegia in the Human Heart During Cardiac Surgery.
Authors: Authors: Heydarpour M, Ejiofor J, Gilfeather M, Stone G, Gorham J, Seidman CE, Seidman JG, Yammine M, Body SC, Aranki SF, Muehlschlegel JD.
Ann Thorac Surg
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