Konrad Hochedlinger

Konrad Hochedlinger, Ph.D.

Professor of Genetics, Massachusetts General Hospital
617-643-2075
Konrad Hochedlinger Website
Feeder-free yet still naïve: improved method for capturing human pluripotent stem cells.
Authors: Authors: Yagi M, Hochedlinger K.
EMBO J
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Post-replicative chromatin accessibility predicts cell fate change.
Authors: Authors: Knudsen TE, Reverón-Gómez N, Biran A, Alcaraz N, Cheloufi S, Hochedlinger K, Brickman JM, Groth A, Stewart-Morgan KR.
Stem Cell Reports
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Metformin inhibits nuclear egress of chromatin fragments in senescence and aging.
Authors: Authors: Kumazawa T, Xu Y, Wang Y, Lee JW, O'Brien TC, Ho CK, Cetinbas M, Weiner A, Hochedlinger K, Sadreyev RI, Bardeesy N, Cheng CW, He B, Dou Z.
Nat Aging
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Modulation of Nudt21 levels reveals dose-dependent roles of alternative polyadenylation in tissue regeneration.
Authors: Authors: Tsopoulidis N, Yagi M, Brumbaugh J, Ito S, López-Soriano V, Morris R, Yoon Y, Messemer KA, Lin KH, Zaniewski EF, Gorelov R, Huebner AJ, Wagers AJ, Hock H, Kramer G, Bukau B, Hoetker MS, Shi Y, Haas W, Hochedlinger K.
Nat Commun
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Transgene-free generation of mouse post-gastrulation whole embryo models solely from naive ESCs and iPSCs.
Authors: Authors: Yilmaz A, Gurhan G, Comar MY, Viukov S, Serfaty I, Gayretli M, Golenchenko S, Lokshtanov D, Ashouokhi S, Polanco A, Berlad I, Ha TW, Aguilera-Castrejon A, Tarazi S, Cohen M, Livnat N, Kumar K, Cholakkal H, Levy N, Yosef N, Khatib N, Kakun RR, Kedmi M, Nachman IB, Keren-Shaul H, Addadi Y, Orenbuch AH, Korovin K, Molchadsky A, Hochedlinger K, Gafni O, Maza I, Novershtern N, Oldak B, Hanna JH.
Cell Stem Cell
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Bivalent chromatin instructs lineage specification during hematopoiesis.
Authors: Authors: Yagi M, Bonilla G, Hoetker MS, Tsopoulidis N, Horng JE, Haggerty C, Meissner A, Sadreyev RI, Hock H, Hochedlinger K.
Cell
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Hematopoietic stem cells undergo bidirectional fate transitions in vivo.
Authors: Authors: Fukushima T, Kristiansen TA, Wong LP, Keyes S, Tanaka Y, Mazzola M, Zhao T, He L, Yagi M, Hochedlinger K, Yamazaki S, Sadreyev RI, Scadden DT.
bioRxiv
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A cellular identity crisis? Plasticity changes during aging and rejuvenation.
Authors: Authors: Gorelov R, Hochedlinger K.
Genes Dev
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Manipulating cell fate through reprogramming: approaches and applications.
Authors: Authors: Yagi M, Horng JE, Hochedlinger K.
Development
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Morphomechanic tuning of ERK by actin-TFII-I? regulates cell identity.
Authors: Authors: Wu Q, Zhang J, Long B, Hu X, de Faria BM, Scalf SM, Karatepe K, Cao W, Tsopoulidis N, Binkercosen A, Yagi M, Weiner A, Kaileh M, De La Cruz EM, Roy AL, Hochedlinger K, Guo S.
bioRxiv
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