Konrad Hochedlinger

Konrad Hochedlinger, Ph.D.

Professor of Genetics, Massachusetts General Hospital

617-643-2075

Publications

Emerging roles of the histone chaperone CAF-1 in cellular plasticity.

Authors: Authors: Cheloufi S, Hochedlinger K.
Curr Opin Genet Dev 2017-10-01
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Epigenetically Aberrant Stroma in MDS Propagates Disease via Wnt/ß-Catenin Activation.

Authors: Authors: Bhagat TD, Chen S, Bartenstein M, Barlowe AT, Von Ahrens D, Choudhary GS, Tivnan P, Amin E, Marcondes AM, Sanders MA, Hoogenboezem RM, Kambhampati S, Ramachandra N, Mantzaris I, Sukrithan V, Laurence R, Lopez R, Bhagat P, Giricz O, Sohal D, Wickrema A, Yeung C, Gritsman K, Aplan P, Hochedlinger K, Yu Y, Pradhan K, Zhang J, Greally JM, Mukherjee S, Pellagatti A, Boultwood J, Will B, Steidl U, Raaijmakers MHGP, Deeg HJ, Kharas MG, Verma A.
Cancer Res 2017-09-15
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Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells.

Authors: Authors: Choi J, Huebner AJ, Clement K, Walsh RM, Savol A, Lin K, Gu H, Di Stefano B, Brumbaugh J, Kim SY, Sharif J, Rose CM, Mohammad A, Odajima J, Charron J, Shioda T, Gnirke A, Gygi S, Koseki H, Sadreyev RI, Xiao A, Meissner A, Hochedlinger K.
Nature 2017-08-10
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Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice.

Authors: Authors: Walsh RM, Shen EY, Bagot RC, Anselmo A, Jiang Y, Javidfar B, Wojtkiewicz GJ, Cloutier J, Chen JW, Sadreyev R, Nestler EJ, Akbarian S, Hochedlinger K.
Nat Commun 2017-05-09
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DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells.

Authors: Authors: Choi J, Clement K, Huebner AJ, Webster J, Rose CM, Brumbaugh J, Walsh RM, Lee S, Savol A, Etchegaray JP, Gu H, Boyle P, Elling U, Mostoslavsky R, Sadreyev R, Park PJ, Gygi SP, Meissner A, Hochedlinger K.
Cell Stem Cell 2017-05-04
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Probabilistic Modeling of Reprogramming to Induced Pluripotent Stem Cells.

Authors: Authors: Liu LL, Brumbaugh J, Bar-Nur O, Smith Z, Stadtfeld M, Meissner A, Hochedlinger K, Michor F.
Cell Rep 2016-12-20
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a-Ketoglutarate Accelerates the Initial Differentiation of Primed Human Pluripotent Stem Cells.

Authors: Authors: TeSlaa T, Chaikovsky AC, Lipchina I, Escobar SL, Hochedlinger K, Huang J, Graeber TG, Braas D, Teitell MA.
Cell Metab 2016-09-13
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Erasure of DNA methylation, genomic imprints, and epimutations in a primordial germ-cell model derived from mouse pluripotent stem cells.

Authors: Authors: Miyoshi N, Stel JM, Shioda K, Qu N, Odajima J, Mitsunaga S, Zhang X, Nagano M, Hochedlinger K, Isselbacher KJ, Shioda T.
Proc Natl Acad Sci U S A 2016-08-23
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Sox2 Suppresses Gastric Tumorigenesis in Mice.

Authors: Authors: Sarkar A, Huebner AJ, Sulahian R, Anselmo A, Xu X, Flattery K, Desai N, Sebastian C, Yram MA, Arnold K, Rivera M, Mostoslavsky R, Bronson R, Bass AJ, Sadreyev R, Shivdasani RA, Hochedlinger K.
Cell Rep 2016-08-16
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Cell reprogramming: Brain versus brawn.

Authors: Authors: Di Stefano B, Hochedlinger K.
Nature 2016-06-16
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