Konrad Hochedlinger

Konrad Hochedlinger, Ph.D.

Professor of Genetics, Massachusetts General Hospital

617-643-2075

Publications

The THO complex regulates pluripotency gene mRNA export and controls embryonic stem cell self-renewal and somatic cell reprogramming.

Authors: Authors: Wang L, Miao YL, Zheng X, Lackford B, Zhou B, Han L, Yao C, Ward JM, Burkholder A, Lipchina I, Fargo DC, Hochedlinger K, Shi Y, Williams CJ, Hu G.
Cell Stem Cell 2013-12-05
View full abstract on Pubmed

Chromatin dynamics during cellular reprogramming.

Authors: Authors: Apostolou E, Hochedlinger K.
Nature 2013-10-24
View full abstract on Pubmed

Removing reprogramming roadblocks: Mbd3 depletion allows deterministic iPSC generation.

Authors: Authors: Brumbaugh J, Hochedlinger K.
Cell Stem Cell 2013-10-03
View full abstract on Pubmed

A variant CRISPR-Cas9 system adds versatility to genome engineering.

Authors: Authors: Walsh RM, Hochedlinger K.
Proc Natl Acad Sci U S A 2013-09-24
View full abstract on Pubmed

Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.

Authors: Authors: Apostolou E, Ferrari F, Walsh RM, Bar-Nur O, Stadtfeld M, Cheloufi S, Stuart HT, Polo JM, Ohsumi TK, Borowsky ML, Kharchenko PV, Park PJ, Hochedlinger K.
Cell Stem Cell 2013-06-06
View full abstract on Pubmed

Sox2 marks epithelial competence to generate teeth in mammals and reptiles.

Authors: Authors: Juuri E, Jussila M, Seidel K, Holmes S, Wu P, Richman J, Heikinheimo K, Chuong CM, Arnold K, Hochedlinger K, Klein O, Michon F, Thesleff I.
Development 2013-04-01
View full abstract on Pubmed

Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination.

Authors: Authors: Wang S, Bates J, Li X, Schanz S, Chandler-Militello D, Levine C, Maherali N, Studer L, Hochedlinger K, Windrem M, Goldman SA.
Cell Stem Cell 2013-02-07
View full abstract on Pubmed

The sox family of transcription factors: versatile regulators of stem and progenitor cell fate.

Authors: Authors: Sarkar A, Hochedlinger K.
Cell Stem Cell 2013-01-03
View full abstract on Pubmed

Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium.

Authors: Authors: Hirata A, Utikal J, Yamashita S, Aoki H, Watanabe A, Yamamoto T, Okano H, Bardeesy N, Kunisada T, Ushijima T, Hara A, Jaenisch R, Hochedlinger K, Yamada Y.
Development 2013-01-01
View full abstract on Pubmed

ISSCR 2013: back to Bean Town.

Authors: Authors: Brack AS, Hochedlinger K.
Stem Cell Reports 2013-01-01
View full abstract on Pubmed