Konrad Hochedlinger, Ph.D.
Professor of Genetics, Massachusetts General Hospital
Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.
Authors: Authors: Apostolou E, Ferrari F, Walsh RM, Bar-Nur O, Stadtfeld M, Cheloufi S, Stuart HT, Polo JM, Ohsumi TK, Borowsky ML, Kharchenko PV, Park PJ, Hochedlinger K.
Cell Stem Cell
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Cell Stem Cell
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Sox2 marks epithelial competence to generate teeth in mammals and reptiles.
Authors: Authors: Juuri E, Jussila M, Seidel K, Holmes S, Wu P, Richman J, Heikinheimo K, Chuong CM, Arnold K, Hochedlinger K, Klein O, Michon F, Thesleff I.
Development
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Development
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Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination.
Authors: Authors: Wang S, Bates J, Li X, Schanz S, Chandler-Militello D, Levine C, Maherali N, Studer L, Hochedlinger K, Windrem M, Goldman SA.
Cell Stem Cell
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Cell Stem Cell
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The sox family of transcription factors: versatile regulators of stem and progenitor cell fate.
Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium.
Authors: Authors: Hirata A, Utikal J, Yamashita S, Aoki H, Watanabe A, Yamamoto T, Okano H, Bardeesy N, Kunisada T, Ushijima T, Hara A, Jaenisch R, Hochedlinger K, Yamada Y.
Development
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Development
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ISSCR 2013: back to Bean Town.
Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency.
Authors: Authors: Hansson J, Rafiee MR, Reiland S, Polo JM, Gehring J, Okawa S, Huber W, Hochedlinger K, Krijgsveld J.
Cell Rep
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Cell Rep
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A molecular roadmap of reprogramming somatic cells into iPS cells.
Authors: Authors: Polo JM, Anderssen E, Walsh RM, Schwarz BA, Nefzger CM, Lim SM, Borkent M, Apostolou E, Alaei S, Cloutier J, Bar-Nur O, Cheloufi S, Stadtfeld M, Figueroa ME, Robinton D, Natesan S, Melnick A, Zhu J, Ramaswamy S, Hochedlinger K.
Cell
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Cell
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Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system.
Authors: Authors: Buckley SM, Aranda-Orgilles B, Strikoudis A, Apostolou E, Loizou E, Moran-Crusio K, Farnsworth CL, Koller AA, Dasgupta R, Silva JC, Stadtfeld M, Hochedlinger K, Chen EI, Aifantis I.
Cell Stem Cell
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Cell Stem Cell
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Reproductive biology: Stem cells bear eggs.