Konrad Hochedlinger, Ph.D.
Professor of Genetics, Massachusetts General Hospital
T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell.
Authors: Authors: Serwold T, Hochedlinger K, Swindle J, Hedgpeth J, Jaenisch R, Weissman IL.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Induced pluripotency: history, mechanisms, and applications.
Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes.
Authors: Authors: Brady BL, Oropallo MA, Yang-Iott KS, Serwold T, Hochedlinger K, Jaenisch R, Weissman IL, Bassing CH.
J Immunol
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J Immunol
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Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells.
Authors: Authors: Polo JM, Liu S, Figueroa ME, Kulalert W, Eminli S, Tan KY, Apostolou E, Stadtfeld M, Li Y, Shioda T, Natesan S, Wagers AJ, Melnick A, Evans T, Hochedlinger K.
Nat Biotechnol
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Nat Biotechnol
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When fibroblasts MET iPSCs.
A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells.
Authors: Authors: Buecker C, Chen HH, Polo JM, Daheron L, Bu L, Barakat TS, Okwieka P, Porter A, Gribnau J, Hochedlinger K, Geijsen N.
Cell Stem Cell
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Cell Stem Cell
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Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells.
Authors: Authors: Stadtfeld M, Apostolou E, Akutsu H, Fukuda A, Follett P, Natesan S, Kono T, Shioda T, Hochedlinger K.
Nature
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Nature
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Your inner healers.
TCR beta feedback signals inhibit the coupling of recombinationally accessible V beta 14 segments with DJ beta complexes.
Authors: Authors: Yang-Iott KS, Carpenter AC, Rowh MA, Steinel N, Brady BL, Hochedlinger K, Jaenisch R, Bassing CH.
J Immunol
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J Immunol
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A reprogrammable mouse strain from gene-targeted embryonic stem cells.
Authors: Authors: Stadtfeld M, Maherali N, Borkent M, Hochedlinger K.
Nat Methods
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Nat Methods
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