Konrad Hochedlinger, Ph.D.
Professor of Genetics, Massachusetts General Hospital
Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells.
Authors: Authors: Ohi Y, Qin H, Hong C, Blouin L, Polo JM, Guo T, Qi Z, Downey SL, Manos PD, Rossi DJ, Yu J, Hebrok M, Hochedlinger K, Costello JF, Song JS, Ramalho-Santos M.
Nat Cell Biol
View full abstract on Pubmed
Nat Cell Biol
View full abstract on Pubmed
Efficient generation of iPS cells from skeletal muscle stem cells.
Authors: Authors: Tan KY, Eminli S, Hettmer S, Hochedlinger K, Wagers AJ.
PLoS One
View full abstract on Pubmed
PLoS One
View full abstract on Pubmed
From MYOD1 to iPS cells.
Modeling Rett syndrome with stem cells.
T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell.
Authors: Authors: Serwold T, Hochedlinger K, Swindle J, Hedgpeth J, Jaenisch R, Weissman IL.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Induced pluripotency: history, mechanisms, and applications.
Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes.
Authors: Authors: Brady BL, Oropallo MA, Yang-Iott KS, Serwold T, Hochedlinger K, Jaenisch R, Weissman IL, Bassing CH.
J Immunol
View full abstract on Pubmed
J Immunol
View full abstract on Pubmed
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells.
Authors: Authors: Polo JM, Liu S, Figueroa ME, Kulalert W, Eminli S, Tan KY, Apostolou E, Stadtfeld M, Li Y, Shioda T, Natesan S, Wagers AJ, Melnick A, Evans T, Hochedlinger K.
Nat Biotechnol
View full abstract on Pubmed
Nat Biotechnol
View full abstract on Pubmed
When fibroblasts MET iPSCs.
A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells.
Authors: Authors: Buecker C, Chen HH, Polo JM, Daheron L, Bu L, Barakat TS, Okwieka P, Porter A, Gribnau J, Hochedlinger K, Geijsen N.
Cell Stem Cell
View full abstract on Pubmed
Cell Stem Cell
View full abstract on Pubmed